Recombinant Human OSTM1 Protein, Myc/DDK-tagged, C13 and N15-labeled

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Recombinant Human OSTM1 Protein, Myc/DDK-tagged, C13 and N15-labeled

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Cat.No. : OSTM1-3891H
Product Overview : OSTM1 MS Standard C13 and N15-labeled recombinant protein (NP_054747) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.
Description : This gene encodes a protein that may be involved in the degradation of G proteins via the ubiquitin-dependent proteasome pathway. The encoded protein binds to members of subfamily A of the regulator of the G-protein signaling (RGS) family through an N-terminal leucine-rich region. This protein also has a central RING finger-like domain and E3 ubiquitin ligase activity. This protein is highly conserved from flies to humans. Defects in this gene may cause the autosomal recessive, infantile malignant form of osteopetrosis.
Source : HEK293
Species : Human
Tag : Myc/DDK
Molecular Mass : 37.3 kDa
AA Sequence : MEPGPTAAQR RCSLPPWLPL GLLLWSGLAL GALPFGSSPH RVFHDLLSEQ QLLEVEDLSL SLLQGGGLGP LSLPPDLPDL DPECRELLLD FANSSAELTG CLVRSARPVR LCQTCYPLFQ QVVSKMDNIS RAAGNTSESQ SCARSLLMAD RMQIVVILSE FFNTTWQEAN CANCLTNNSE ELSNSTVYFL NLFNHTLTCF EHNLQGNAHS LLQTKNYSEV CKNCREAYKT LSSLYSEMQK MNELENKAEP GTHLCIDVED AMNITRKLWS RTFNCSVPCS DTVPVIAVSV FILFLPVVFY LSSFLHSEQK KRKLILPKRL KSSTSFANIQ ENSNTRTRPL EQKLISEEDL AANDILDYKD DDDKV
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 3 months from receipt of products under proper storage and handling conditions.
Storage : Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
Concentration : 50 μg/mL as determined by BCA
Storage Buffer : 100 mM glycine, 25 mM Tris-HCl, pH 7.3.
SDS-PAGE :

Gene Name : OSTM1 osteopetrosis associated transmembrane protein 1 [ Homo sapiens (human) ]
Official Symbol : OSTM1
Synonyms : OSTM1; osteopetrosis associated transmembrane protein 1; osteopetrosis-associated transmembrane protein 1; GL; HSPC019; grey-lethal osteopetrosis; GAIP-interacting protein N terminus; GIPN; OPTB5;
Gene ID : 28962
mRNA Refseq : NM_014028
Protein Refseq : NP_054747
MIM : 607649
UniProt ID : Q86WC4

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