Recombinant Human PA1, His-tagged

• Cat.No.: PA1-3530H
• Product Overview: Recombinant human PA1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques (1-254aa).

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Description: PA1 is a component of a Set1-like multiprotein histone methyltransferase complex. It interacts with PAXIP1/PTIP; the interaction is direct and is required for the association with the rest of the PTIP complex. This protein plays a critical role in maintaining genome stability, condensation of chromatin and progression through mitosis.
• Form: Liquid. In 20mM Tris-HClbuffer(pH 8.0) containing 10% glycerol, 2mM DTT, 0.1M NaCl.
• Molecular Weight: 29.9 kDa (274aa),confirmed by MALDI-TOF(Molecular weight on SDS-PAGE will appear higher)
• Purity: >85 % by SDS -PAGE
• Concentration: 1 mg/ml (determined by Bradford assay)
• Sequences of amino acids: MGSSHHHHHH SSGLVPRGSH MSLARGHGDT AASTAAPLSE EGEVTSGLQA LAVEDTGGPS ASAGKAEDEG EGGREETERE GSGGEEAQGE VPSAGGEEPA EEDSEDWCVP CSDEEVELPA DGQPWMPPPS EIQRLYELLA AHGTLELQAE ILPRRPPTPE AQSEEERSDE EPEAKEEEEE KPHMPTEFDF DDEPVTPKDS LIDRRRTPGS SARSQKREAR LDKVLSDMKR HKKLEEQILR TGRDLFSLDS EDPSPASPPL RSSGSSLFPR QRKY
• Storage: Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C.Avoid repeated freezing and thawing cycles.

Gene Information

• Gene Name: C16orf53 chromosome 16 open reading frame 53 [ Homo sapiens ]
• Synonyms: C16orf53;PA1; GAS; MGC4606; FLJ22459; PAXIP1-associated protein 1; PTIP-associated 1 protein; PTIP-associated protein 1; glutamate-rich coactivator interacting with SRC1/NCOA1
• Gene ID: 79447
• mRNA Refseq: NM_024516
• Protein Refseq: NP_078792
• MIM: 612033
• UniProt ID: Q9BTK6
• Chromosome Location: 16p11.2