"PADI2" Related Products

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Recombinant Human PADI2 Protein, His/GST-tagged

Cat.No.: PADI2-311H
Product Overview: Recombinant Human PADI2(Met1~ Thr300) fused with His/GST tag at N-terminal was expressed in E. coli.
Description: This gene encodes a member of the peptidyl arginine deiminase family of enzymes, which catalyze the post-translational deimination of proteins by converting arginine residues into citrullines in the presence of calcium ions. The family members have distinct substrate specificities and tissue-specific expression patterns. The type II enzyme is the most widely expressed family member. Known substrates for this enzyme include myelin basic protein in the central nervous system and vimentin in skeletal muscle and macrophages. This enzyme is thought to play a role in the onset and progression of neurodegenerative human disorders, including Alzheimer disease and multiple sclerosis, and it has also been implicated in glaucoma pathogenesis. This gene exists in a cluster with four other paralogous genes.
Source: E. coli
Species: Human
Tag : His/GST
Form: PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
Molecular Mass: 63.9kDa
Protein length: Met1~ Thr300
Endotoxin: <1.0EU per 1µg (determined by the LAL method)
Purity: > 92%
Applications: Positive Control; Immunogen; SDS-PAGE; WB.
If bio-activity of the protein is needed, please check active protein.
Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
Reconstitution: Reconstitute in PBS or others.
Gene Name: PADI2 peptidyl arginine deiminase, type II [ Homo sapiens ]
Official Symbol: PADI2
Synonyms: PADI2; peptidyl arginine deiminase, type II; protein-arginine deiminase type-2; KIAA0994; PDI2; protein arginine deiminase; peptidylarginine deiminase II; peptidlyarginine deiminase type II; protein-arginine deiminase type II; PAD2; PAD-H19;
Gene ID: 11240
mRNA Refseq: NM_007365
Protein Refseq: NP_031391
MIM: 607935
UniProt ID: Q9Y2J8

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Optional requirements on this protein    +Expand
C-fusion    N-fusion   Non-tagged
His    GST   Fc   Others
<1.0 eu/μg    <0.1 eu/μg   <0.01 eu/μg   Not required
Monomer Isolation    Dimer Isolation    Not required
>80% by SDS-PAGE    >90% by SDS-PAGE   >95% by SDS-PAGE   Others

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