Recombinant Human PADI4 Protein, His-tagged
Cat.No. : | PADI4-293H |
Product Overview : | Recombinant human PADI4 (Met1-Pro663) was expressed with a polyhistidine tag at the N-terminus. |
- Specification
- Gene Information
- Related Products
Source : | Baculovirus-Insect Cells |
Species : | Human |
Tag : | His |
Predicted N Terminal : | Met |
Form : | Lyophilized from sterile 20 mM Tris, 500 mM NaCl, 10 % glycerol, pH 7.4, 5%~8% trehalose and mannitol. |
Molecular Mass : | The recombinant human PADI4 consists 663 amino acids and predicts a molecular mass of 74 kDa. |
Endotoxin : | < 1.0 EU per μg of the protein as determined by the LAL method. |
Purity : | >95 % as determined by SDS-PAGE. |
Stability : | Samples are stable for up to twelve months from date of receipt at -70ºC. |
Storage : | Store it under sterile conditions at -20ºC~-70ºC. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
Reconstitution : | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.25 ug/ul. Centrifuge the vial at 4℃ before opening to recover the entire contents. |
Gene Name : | PADI4 peptidyl arginine deiminase, type IV [ Homo sapiens ] |
Official Symbol : | PADI4 |
Synonyms : | PADI4; peptidyl arginine deiminase, type IV; PADI5, peptidyl arginine deiminase, type V; protein-arginine deiminase type-4; PAD; PDI4; PDI5; HL-60 PAD; PADI-H protein; protein-arginine deiminase type IV; peptidyl arginine deiminase, type V; PAD4; PADI5; |
Gene ID : | 23569 |
mRNA Refseq : | NM_012387 |
Protein Refseq : | NP_036519 |
MIM : | 605347 |
UniProt ID : | Q9UM07 |
Chromosome Location : | 1p36.13 |
Pathway : | protein citrullination, organism-specific biosystem; protein citrullination, conserved biosystem; |
Products Types
◆ Recombinant Protein | ||
PADI4-0219H | Recombinant Human PADI4 Protein (A2-P663), His tagged | +Inquiry |
PADI4-1599H | Recombinant Human PADI4 Protein, His (Fc)-Avi-tagged | +Inquiry |
PADI4-6466M | Recombinant Mouse PADI4 Protein, His (Fc)-Avi-tagged | +Inquiry |
Padi4-038M | Recombinant Mouse Padi4 Protein, His-tagged | +Inquiry |
PADI4-114H | Recombinant Human PADI4 Protein, His-tagged | +Inquiry |
◆ Lysates | ||
PADI4-630HCL | Recombinant Human PADI4 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
- Q&As
- Reviews
Q&As (7)
Ask a questionPADI4 is predominantly expressed in various tissues, including synovial tissues, immune cells, and certain epithelial cells.
PADI4 plays a crucial role in citrullination, a process that converts arginine residues to citrulline, influencing protein structure and function.
Peptidyl arginine deiminase 4 (PADI4) primarily functions in cellular processes, contributing to the post-translational modification of proteins through citrullination.
In the regulation of immune responses, PADI4 is implicated in autoimmune diseases such as rheumatoid arthritis, where it contributes to autoantibody generation.
Dysregulation or abnormal expression of PADI4 is associated with autoimmune disorders, particularly rheumatoid arthritis.
There are potential therapeutic implications related to targeting PADI4 in autoimmune disorders, making it a focus for drug development.
Specific substrates of PADI4 include histones and other proteins, impacting cellular processes like gene regulation and signaling pathways.
Customer Reviews (3)
Write a reviewThe minimal variation across different batches enhanced the repeatability of our results.
The product's role in promoting collaboration and teamwork positively impacted the quality of our research.
The product's compatibility with various instruments and techniques promoted teamwork in our interdisciplinary projects.
Ask a Question for All PADI4 Products
Required fields are marked with *
My Review for All PADI4 Products
Required fields are marked with *
Inquiry Basket