Recombinant Human PAH Protein, His-tagged

• Cat.No.: PAH-260H
• Product Overview: Recombinant Human PAH Protein(NP_000268.1) fused with His tag, was expressed in HEK293.

Specification

• Species: Human
• Source: HEK293
• Tag: His
• Protein Length: Wild type full length
• Description: This gene encodes a member of the biopterin-dependent aromatic amino acid hydroxylase protein family. The encoded phenylalanine hydroxylase enzyme hydroxylates phenylalanine to tyrosine and is the rate-limiting step in phenylalanine catabolism. Deficiency of this enzyme activity results in the autosomal recessive disorder phenylketonuria.
• Form: Supplied as a 0.2 μm filtered solution in PBS (pH 7.4)
• Endotoxin: <1EU per ug (determined by the LAL method)
• Purity: >= 90% as determined by SDS-PAGE
• Storage: Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
• Concentration: 0.5 mg/ml

Gene Information

• Gene Name: PAH phenylalanine hydroxylase [ Homo sapiens (human) ]
• Official Symbol: PAH
• Synonyms: PH; PKU; PKU1
• Gene ID: 5053
• mRNA Refseq: NM_000277.3
• Protein Refseq: NP_000268.1
• MIM: 612349
• UniProt ID: P00439