Recombinant Human PAOX Protein, MYC/DDK-tagged

• Cat.No.: PAOX-251H
• Product Overview: Recombinant human PAOX protein, fused to MYC/DDK tag at C-terminus, was expressed in HEK293.

Specification

• Species: Human
• Source: HEK293
• Tag: DDK&Myc
• Description: Flavoenzyme which catalyzes the oxidation of N(1)-acetylspermine to spermidine and is thus involved in the polyamine back-conversion. Can also oxidize N(1)-acetylspermidine to putrescine. Substrate specificity: N(1)-acetylspermine = N(1)-acetylspermidine > N(1),N(12)-diacylspermine >> spermine. Does not oxidize spermidine. Plays an important role in the regulation of polyamine intracellular concentration and has the potential to act as a determinant of cellular sensitivity to the antitumor polyamine analogs. [UniProtKB/Swiss-Prot Function]
• Form: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
• Molecular Mass: 34.5 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: polyamine oxidase [ Homo sapiens ]
• Official Symbol: PAOX
• Synonyms: PAO; PAO
• Gene ID: 196743
• mRNA Refseq: NM_152911.2
• Protein Refseq: NP_690875.1
• UniProt ID: Q6QHF9