Recombinant Human PARP1 protein, His-tagged
Cat.No. : | PARP1-01H |
Product Overview : | Recombinant Human PARP1 protein(NP_001609.2), fused to His-tag, was expressed in E. coli. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes. |
Source : | E. coli |
Species : | Human |
Tag : | His |
Form : | PBS, pH 7.0 |
Molecular Mass : | The protein has a calculated MW of 41.6 kDa. |
AA Sequence : | MNHKVHHHHHHHHHHMKSKLPKPVQ DLIKMIFDVESMKKAMVEYEIDLQK MPLGKLSKRQIQAAYSILSEVQQAV SQGSSDSQILDLSNRFYTLIPHDFG MKKPPLLNNADSVQAKAEMLDNLLD IEVAYSLLRGGSDDSSKDPIDVNYE KLKTDIKVVDRDSEEAEIIRKYVKN THATTHNAYDLEVIDIFKIEREGEC QRYKPFKQLHNRRLLWHGSRTTNFA GILSQGLRIAPPEAPVTGYMFGKGI YFADMVSKSANYCHTSQGDPIGLIL LGEVALGNMYELKHASHISKLPKGK HSVKGLGKTTPDPSANISLDGVDVP LGTGISSGVNDTSLLYNEYIVYDIA QVNLKYLLKLKFNFKTSLW |
Purity : | >= 95% by SDS-PAGE |
Storage : | Store it under sterile conditions at -20 to -80 ºC. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
Concentration : | 0.5 mg/ml |
Gene Name : | PARP1 poly(ADP-ribose) polymerase 1 [ Homo sapiens (human) ] |
Official Symbol : | PARP1 |
Synonyms : | PARP; PPOL; ADPRT; ARTD1; ADPRT1; PARP-1; ADPRT 1; pADPRT-1 |
Gene ID : | 142 |
mRNA Refseq : | NM_001618.4 |
Protein Refseq : | NP_001609.2 |
MIM : | 173870 |
UniProt ID : | P09874 |
Products Types
◆ Recombinant Protein | ||
PARP1-010H | Active Recombinant Human PARP1 Protein, GST-tagged | +Inquiry |
PARP1-59H | Recombinant Human PARP1 Protein | +Inquiry |
PARP1-3938R | Recombinant Rat PARP1 Protein, His (Fc)-Avi-tagged | +Inquiry |
PARP1-075H | Recombinant Human PARP1 Protein, MYC/DDK-tagged, C13 and N15-labeled | +Inquiry |
PARP1-3796H | Recombinant Human PARP1 Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
PARP1-710HCL | Recombinant Human PARP1 cell lysate | +Inquiry |
PARP1-514MCL | Recombinant Mouse PARP1 cell lysate | +Inquiry |
◆ Assay kits | ||
Kit-1794 | PARP1 Colorimetric Assay Kit | +Inquiry |
Kit-1792 | PARP1 Chemiluminescent Assay Kit | +Inquiry |
Kit-1793 | PARP1 Chemiluminescent Assay Kit (384-well) | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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