Recombinant Human PCBP1, His-tagged
Cat.No. : | PCBP1-2314H |
Product Overview : | Recombinant human PCBP1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. |
- Specification
- Gene Information
- Related Products
Description : | PCBP1 appears to be multifunctional. It along with PCBP-2 and hnRNPK corresponds to the major cellular poly(rC)-binding protein. It contains three K-homologous (KH) domains which may be involved in RNA binding. This protein together with PCBP-2 also functions as translational coactivators of poliovirus RNA via a sequence-specific interaction with stem-loop IV of the IRES and promotes poliovirus RNA replication by binding to its 5"-terminal cloverleaf structure. It has also been implicated in translational control of the 15-lipoxygenase mRNA, human Papillomavirus type 16 L2 mRNA, and hepatitis A virus RNA. PCBP1 is also suggested to play a part in formation of a sequence-specific alpha-globin mRNP complex which is associated with alpha-globin mRNA stability. |
Source : | E. coli |
Species : | Human |
Tag : | His |
Form : | Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 20% glycerol, 1mM DTT |
Molecular Mass : | 19.6 kDa |
Protein length : | 186aa |
AA Sequence : | MGSSHHHHHH SSGLVPRGSH MGSMDAGVTE SGLNVTLTIR LLMHGKEVGS IIGKKGESVK RIREESGARI NISEGNCPER IITLTGPTNA IFKAFAMIID KLEEDINSSM TNSTAASRPP VTLRLVVPAT QCGSLIGKGG CKIKEIREST GAQVQVAGDM LPNSTERAIT IAGVPQSVTE CVKQIC |
Purity : | >85% by SDS - PAGE |
Applications : | SDS-PAGE |
Storage : | Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles. |
Concentration : | 1 mg/ml |
Gene Name : | PCBP1 poly(rC) binding protein 1 [ Homo sapiens ] |
Official Symbol : | PCBP1 |
Synonyms : | PCBP1; poly(rC) binding protein 1; poly(rC)-binding protein 1; heterogeneous nuclear ribonucleoprotein E1; hnRNP E1; hnRNP X; HNRPE1; HNRPX; alpha-CP1; nucleic acid-binding protein SUB2.3; heterogenous nuclear ribonucleoprotein X; heterogenous nuclear ribonucleoprotein E1; hnRNP-X; hnRNP-E1; |
Gene ID : | 5093 |
mRNA Refseq : | NM_006196 |
Protein Refseq : | NP_006187 |
MIM : | 601209 |
UniProt ID : | Q15365 |
Chromosome Location : | 2p13-p12 |
Pathway : | Gene Expression, organism-specific biosystem; Processing of Capped Intron-Containing Pre-mRNA, organism-specific biosystem; Spliceosome, organism-specific biosystem; Spliceosome, conserved biosystem; mRNA Splicing, organism-specific biosystem; mRNA Splicing - Major Pathway, organism-specific biosystem; |
Function : | DNA binding; RNA binding; protein binding; single-stranded DNA binding; |
Products Types
◆ Recombinant Protein | ||
PCBP1-6532M | Recombinant Mouse PCBP1 Protein, His (Fc)-Avi-tagged | +Inquiry |
Pcbp1-4696M | Recombinant Mouse Pcbp1 Protein, Myc/DDK-tagged | +Inquiry |
PCBP1-1172P | Recombinant Pig PCBP1 Protein, His-tagged | +Inquiry |
PCBP1-901H | Recombinant Human PCBP1 protein, MYC/DDK-tagged | +Inquiry |
PCBP1-327H | Recombinant Human PCBP1 Protein, His-tagged | +Inquiry |
◆ Lysates | ||
PCBP1-3403HCL | Recombinant Human PCBP1 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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