Recombinant Human PCDHGA6 Protein, MYC/DDK-tagged

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Recombinant Human PCDHGA6 Protein, MYC/DDK-tagged

PCDHGA6 Related Products

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Cat.No. : PCDHGA6-542H
Product Overview : Recombinant human PCDHGA6 protein, fused to MYC/DDK tag at C-terminus, was expressed in HEK293.
Description : This gene is a member of the protocadherin gamma gene cluster, one of three related clusters tandemly linked on chromosome five. These gene clusters have an immunoglobulin-like organization, suggesting that a novel mechanism may be involved in their regulation and expression. The gamma gene cluster includes 22 genes divided into 3 subfamilies. Subfamily A contains 12 genes, subfamily B contains 7 genes and 2 pseudogenes, and the more distantly related subfamily C contains 3 genes. The tandem array of 22 large, variable region exons are followed by a constant region, containing 3 exons shared by all genes in the cluster. Each variable region exon encodes the extracellular region, which includes 6 cadherin ectodomains and a transmembrane region. The constant region exons encode the common cytoplasmic region. These neural cadherin-like cell adhesion proteins most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been described for the gamma cluster genes. [provided by RefSeq, Jul 2008].
Source : HEK293
Species : Human
Tag : MYC/DDK
Form : 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
Molecular Mass : 97.7 kDa
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration : >50 ug/mL as determined by microplate BCA method
Gene Name : protocadherin gamma subfamily A, 6[ Homo sapiens ]
Official Symbol : PCDHGA6
Synonyms : PCDH-GAMMA-A6; PCDH-GAMMA-A6
Gene ID : 56109
mRNA Refseq : NM_018919.2
Protein Refseq : NP_061742.1
MIM : 606293
UniProt ID : Q9Y5G7

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