Recombinant Human PCDHGC5 Protein, Myc/DDK-tagged, C13 and N15-labeled PCDHGC5-6107H

Specification Gene Information Related Products

Cat.No. :	PCDHGC5-6107H
Product Overview :	PCDHGC5 MS Standard C13 and N15-labeled recombinant protein (NP_115783) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.
Description :	This gene is a member of the protocadherin gamma gene cluster, one of three related clusters tandemly linked on chromosome five. These gene clusters have an immunoglobulin-like organization, suggesting that a novel mechanism may be involved in their regulation and expression. The gamma gene cluster includes 22 genes divided into 3 subfamilies. Subfamily A contains 12 genes, subfamily B contains 7 genes and 2 pseudogenes, and the more distantly related subfamily C contains 3 genes. The tandem array of 22 large, variable region exons are followed by a constant region, containing 3 exons shared by all genes in the cluster. Each variable region exon encodes the extracellular region, which includes 6 cadherin ectodomains and a transmembrane region. The constant region exons encode the common cytoplasmic region. These neural cadherin-like cell adhesion proteins most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been described for the gamma cluster genes.
Source :	HEK293
Species :	Human
Tag :	Myc/DDK
Molecular Mass :	95.1 kDa
AA Sequence :	MGPKTLPQLA GKWQVLCMLS LCCWGWVSGQ LRYSVVEESE PGTLVGNVAQ DLGLKMTDLL SRRLQLGSEE NGRYFSLSLM SGALAVNQKI DRESLCGAST SCLLPVQVVT EHPLELIRVE VEILDLNDNS PSFATPEREM RISESAASGA RFPLDSAQDP DVGTNTVSFY TLSPNSHFSL NVKTLKDGKP FPELVLEQQL DREAQARHQL VLTAVDGGTP ARSGTTLISV IVLDINDNAP TFQSSVLRVG IPENAPIGTL LLRLNATDPD EGTNGQLDYS FGDHTSEAVR NLFGLDPSSG AIHVLGPIDF EESRFYEIHA RARDQGQPAM EGHCVIQVDV GDVNDNAPEV LLASLANPVL ESTPVGTVVG LFNVRDRDSG RNGEVSLDIS PDLPFQIKPS ENHYSLLTSQ PLDREATSHY IIELLASDAG SPSLHKHLTI RLNISDVNDN APRFNQQLYT AYILENRPPG SLLCTVAASD PDTGDNARLT YSIVGNQVQG APASSFVYVN PEDGRIFAQR TFDYELLQML QIVVGVRDSG SPPLHANTSL HVFVLDENDN APAVLHPRPG WEHSAPQRLP RSAPPGSLVT KVTAVDADAG HNAWLSYSLL PQSTAPGLFL VSTHTGEVRT ARALLEDDSD TQQVVVLVRD NGDPSLSSTA TVLLVLEDED PEEMPKSSDF LIHPPERSDL TLYLIVALAT VSLLSLVTFT FLSAKCLQGN ADGDGGGGQC CRRQDSPSPD FYKQSSPNLQ VSSDGTLKYM EVTLRPTDSQ SHCYRTCFSP ASDGSDFTFL RPLSVQQPTA LALEPDAIRS RSNTLRERSQ VRGSAPPRAT PGGGTGEAAR PHKGLNLHPL LSGRLGRWLR STRFSGSLDR LRGTRVADTR TRPLEQKLIS EEDLAANDIL DYKDDDDKV
Purity :	> 80% as determined by SDS-PAGE and Coomassie blue staining
Stability :	Stable for 3 months from receipt of products under proper storage and handling conditions.
Storage :	Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
Concentration :	50 μg/mL as determined by BCA
Storage Buffer :	100 mM glycine, 25 mM Tris-HCl, pH 7.3.
SDS-PAGE :

Gene Name :	PCDHGC5 protocadherin gamma subfamily C, 5 [ Homo sapiens (human) ]
Official Symbol :	PCDHGC5
Synonyms :	PCDHGC5; protocadherin gamma subfamily C, 5; protocadherin gamma-C5; PCDH GAMMA C5; PCDH-GAMMA-C5; MGC138286; MGC138288;
Gene ID :	56097
mRNA Refseq :	NM_032407
Protein Refseq :	NP_115783
MIM :	606306
UniProt ID :	Q9Y5F6