Recombinant Human PCNP, His-tagged

• Cat.No.: PCNP-3605H
• Product Overview: Recombinant human PCNP protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Description: PCNP (PEST proteolytic signal containing nuclear protein) is a nuclear protein implied to play a role in cell cycle regulation and tumorigenesis. This protein is ubiquitinated post-translationally by NIRF, an ubiquitin ligase. PCNP exsists as three isoforms produced by alternative splicing events and may be involved in cell cycle regulation.
• Form: Liquid. In 20mM Tris-HCl buffer(pH 8.0) containing 10% glycerol, 1mM DTT
• Molecular Weight: 21.5 kDa (202aa), confirmed by MALDI-TOF
• Purity: >95 % by SDS -PAGE
• Concentration: 1 mg/ml (determined by BCA)
• Sequences of amino acids: MGSSHHHHHH SSGLVPRGSH MGSHMADGKA GDEKPEKSQR AGAAGGPEEE AEKPVKTKTV SSSNGGESSS RSAEKRSAEE EAADLPTKPT KISKFGFAIG SQTTKKASAI SIKLGSSKPK ETVPTLAPKT LSVAAAFNED EDSEPEEMPP EAKMRMKNIG RDTPTSAGPN SFNKGKHGFS DNQKLWERNI KSHLGNVHDQ DN
• Storage: Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.

Gene Information

• Gene Name: PCNP PEST proteolytic signal containing nuclear protein [ Homo sapiens ]
• Official Symbol: PCNP
• Synonyms: PCNP; DKFZp781I24156; OTTHUMP00000214092; PEST-containing nuclear protein; PEST proteolytic signal-containing nuclear protein
• Gene ID: 57092
• mRNA Refseq: NM_020357
• Protein Refseq: NP_065090
• UniProt ID: Q8WW12
• Chromosome Location: 3q12.3
• Function: protein binding