Recombinant Human PCSK9 Protein, His-tagged
| Cat.No. : | PCSK9-135H |
| Product Overview : | Active recombinant N-terminal His-tagged human PCSK9 protein (31-692) isolated from a HEK293 overexpression system. |
- Specification
- Gene Information
- Related Products
| Description : | This gene encodes a member of the subtilisin-like proprotein convertase family, which includes proteases that process protein and peptide precursors trafficking through regulated or constitutive branches of the secretory pathway. The encoded protein undergoes an autocatalytic processing event with its prosegment in the ER and is constitutively secreted as an inactive protease into the extracellular matrix and trans-Golgi network. It is expressed in liver, intestine and kidney tissues and escorts specific receptors for lysosomal degradation. It plays a role in cholesterol and fatty acid metabolism. Mutations in this gene have been associated with autosomal dominant familial hypercholesterolemia. Alternative splicing results in multiple transcript variants. |
| Source : | HEK293 |
| Species : | Human |
| Tag : | His |
| Form : | Lyophilized |
| Molecular Mass : | 71 kDa (~16 & 63 kDa purified) |
| Protein length : | 31-692 |
| Purity : | ≥90% as determined by SDS-PAGE |
| Stability : | ≥ 6 months |
| Storage : | At -80 centigrade. |
| Storage Buffer : | PBS, pH 7.4, with 30% sucrose |
| Gene Name : | PCSK9 proprotein convertase subtilisin/kexin type 9 [ Homo sapiens (human) ] |
| Official Symbol : | PCSK9 |
| Synonyms : | PCSK9; proprotein convertase subtilisin/kexin type 9; FH3; PC9; FHCL3; NARC1; LDLCQ1; NARC-1; HCHOLA3; proprotein convertase subtilisin/kexin type 9; convertase subtilisin/kexin type 9 preproprotein; neural apoptosis regulated convertase 1; subtilisin/kexin-like protease PC9 |
| Gene ID : | 255738 |
| mRNA Refseq : | NM_174936 |
| Protein Refseq : | NP_777596 |
| MIM : | 607786 |
| UniProt ID : | Q8NBP7 |
Products Types
| ◆ Recombinant Protein | ||
| PCSK9-3152R | Recombinant Rhesus Macaque PCSK9 Protein, His (Fc)-Avi-tagged | +Inquiry |
| Pcsk9-265M | Recombinant Mouse PCSK9 Protein, His-tagged(C-ter) | +Inquiry |
| PCSK9-035H | Recombinant Human PCSK9 Protein, MYC/DDK-tagged, C13 and N15-labeled | +Inquiry |
| PCSK9-406C | Recombinant Chinese hamster PCSK9 Protein, His-tagged | +Inquiry |
| PCSK9-411H | Recombinant Human PCSK9 Protein, Strep-tagged | +Inquiry |
| ◆ Lysates | ||
| PCSK9-2875HCL | Recombinant Human PCSK9 cell lysate | +Inquiry |
| PCSK9-2306RCL | Recombinant Rat PCSK9 cell lysate | +Inquiry |
| PCSK9-2564MCL | Recombinant Mouse PCSK9 cell lysate | +Inquiry |
| ◆ Assay kits | ||
| Kit-1808 | PCSK9-LDLR TR-FRET Assay Kit | +Inquiry |
| Kit-1807 | PCSK9[Biotinylated]-LDLR Binding Assay Kit | +Inquiry |
| Kit-1806 | PCSK9(D374T)-LDLR TR-FRET Assay Kit | +Inquiry |
| Kit-0666 | PCSK9-LDLR in vitro Binding Assay Kit | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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