Recombinant Human PDE1A Protein, Myc/DDK-tagged, C13 and N15-labeled

Cat.No. : PDE1A-1787H
Product Overview : PDE1A MS Standard C13 and N15-labeled recombinant protein (NP_005010) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.
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Description : Cyclic nucleotide phosphodiesterases (PDEs) play a role in signal transduction by regulating intracellular cyclic nucleotide concentrations through hydrolysis of cAMP and/or cGMP to their respective nucleoside 5-prime monophosphates. Members of the PDE1 family, such as PDE1A, are Ca(2+)/calmodulin-dependent PDEs (CaM-PDEs) that are activated by calmodulin in the presence of Ca(2+).
Source : HEK293
Species : Human
Tag : Myc/DDK
Molecular Mass : 62.3 kDa
AA Sequence : MGSSATEIEELENTTFKYLTGEQTE KMWQRLKGILRCLVKQLERGDVNVV DLKKNIEYAASVLEAVYIDETRRLL DTEDELSDIQTDSVPSEVRDWLAST FTRKMGMTKKKPEEKPKFRSIVHAV QAGIFVERMYRKTYHMVGLAYPAAV IVTLKDVDKWSFDVFALNEASGEHS LKFMIYELFTRYDLINRFKIPVSCL ITFAEALEVGYSKYKNPYHNLIHAA DVTQTVHYIMLHTGIMHWLTELEIL AMVFAAAIHDYEHTGTTNNFHIQTR SDVAILYNDRSVLENHHVSAAYRLM QEEEMNILINLSKDDWRDLRNLVIE MVLSTDMSGHFQQIKNIRNSLQQPE GIDRAKTMSLILHAADISHPAKSWK LHYRWTMALMEEFFLQGDKEAELGL PFSPLCDRKSTMVAQSQIGFIDFIV EPTFSLLTDSTEKIVIPLIEEASKA ETSSYVASSSTTIVGLHIADALRRS NTKGSMSDGSYSPDYSLAAVDLKSF KNNLVDIIQQNKERWKELAAQGESD LHKNSEDLVNAEEKHDETHSTRTRP LEQKLISEEDLAANDILDYKDDDDK V
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 3 months from receipt of products under proper storage and handling conditions.
Storage : Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
Concentration : 50 μg/mL as determined by BCA
Storage Buffer : 100 mM glycine, 25 mM Tris-HCl, pH 7.3.
Gene Name : PDE1A phosphodiesterase 1A [ Homo sapiens (human) ]
Official Symbol : PDE1A
Synonyms : PDE1A; phosphodiesterase 1A, calmodulin-dependent; calcium/calmodulin-dependent 3,5-cyclic nucleotide phosphodiesterase 1A; hCam-1; cam-PDE 1A; 61 kDa Cam-PDE; phosphodiesterase-1A; calmodulin-dependent phosphodiesterase; 3,5 cyclic nucleotide phosphodiesterase; calcium/calmodulin-stimulated cyclic nucleotide phosphodiesterase; HCAM1; HSPDE1A; MGC26303;
Gene ID : 5136
mRNA Refseq : NM_005019
Protein Refseq : NP_005010
MIM : 171890
UniProt ID : P54750

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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