Recombinant Human PDE1C Protein, His/GST-tagged
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Cat.No. : | PDE1C-03H Optional Service: Optional requirements on this protein |
Product Overview : | Recombinant human PDE1C protein (1-634) with a N-teminus His/GST-tag was expressed in insect cells. |
Description : | This gene encodes an enzyme that belongs to the 3'5'-cyclic nucleotide phosphodiesterase family. Members of this family catalyze hydrolysis of the cyclic nucleotides, cyclic adenosine monophosphate and cyclic guanosine monophosphate, to the corresponding nucleoside 5'-monophosphates. The enzyme encoded by this gene regulates proliferation and migration of vascular smooth muscle cells, and neointimal hyperplasia. This enzyme also plays a role in pathological vascular remodeling by regulating the stability of growth factor receptors, such as PDGF-receptor-beta. |
Source : | Insect cell |
Species : | Human |
Tag : | His/GST |
Form : | Lyophilized from sterile 20 mM Tris, 500 mM NaCl, pH 7.4, 10% glycerol, 3 mM DTT |
Molecular Mass : | 100 kDa |
Protein length : | 1-634 |
Endotoxin : | <1.0 EU/μg of the protein as determined by the LAL method |
Purity : | ≥85 % as determined by SDS-PAGE |
Stability : | ≥ 1 year |
Storage : | Store at -80 centigrade |
SDS-PAGE Analysis of PDE1C1 : |
![]() Lane 1: MW Markers, Lane 2: PDE1C1, SDS-PAGE Analysis of PDE1C1. This protein has a calculated molecular weight of 100 kDa. It has an apparent molecular weight of approximately 97 kDa by SDS-PAGE under reducing condions. |
Gene Name : | PDE1C phosphodiesterase 1C [ Homo sapiens (human) ] |
Official Symbol : | PDE1C |
Synonyms : | PDE1C; phosphodiesterase 1C; Hcam3; DFNA74; hCam-3; cam-PDE 1C; calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C; 3',5'-cyclic-AMP phosphodiesterase; 3',5'-cyclic-GMP phosphodiesterase; Human 3',5' cyclic nucleotide phosphodiesterase (HSPDE1C1A); phosphodiesterase 1C, calmodulin-dependent 70kDa |
Gene ID : | 5137 |
mRNA Refseq : | NM_001191056 |
Protein Refseq : | NP_001177985 |
MIM : | 602987 |
UniProt ID : | Q14123 |
◆ Recombinant Protein
PDE1C-047H | Recombinant Human PDE1C Protein, His/GST-tagged | +Inquiry |
PDE1C-3987R | Recombinant Rat PDE1C Protein, His (Fc)-Avi-tagged | +Inquiry |
PDE1C-1612 | Recombinant Human PDE1C protein, GST-tagged | +Inquiry |
Pde1c-4463R | Recombinant Rat Pde1c protein, His-tagged | +Inquiry |
PDE1C-146H | Recombinant Human PDE1C Protein, His-tagged | +Inquiry |
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◆ Lysates
PDE1C-001HCL | Recombinant Human PDE1C cell lysate | +Inquiry |
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◆ Assay kits
Kit-1828 | PDE1C Assay Kit I | +Inquiry |
Kit-1831 | PDE1C TR-FRET Assay Kit | +Inquiry |
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Pde10aPDE11APDE1APDE1BPde1cPDE2APDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE6BPDE6CPDE6DPDE7APDE7BPDE8APDE9APDE4DIPPDE12PDE6APDE8BPDE6GPDE6H
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