Recombinant Human PDE1C Protein, His/GST-tagged PDE1C-03H

Recombinant Human PDE1C Protein, His/GST-tagged

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Recombinant Human PDE1C Protein, His/GST-tagged

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Cat.No. : PDE1C-03H
Product Overview : Recombinant human PDE1C protein (1-634) with a N-teminus His/GST-tag was expressed in insect cells.
Description : This gene encodes an enzyme that belongs to the 3'5'-cyclic nucleotide phosphodiesterase family. Members of this family catalyze hydrolysis of the cyclic nucleotides, cyclic adenosine monophosphate and cyclic guanosine monophosphate, to the corresponding nucleoside 5'-monophosphates. The enzyme encoded by this gene regulates proliferation and migration of vascular smooth muscle cells, and neointimal hyperplasia. This enzyme also plays a role in pathological vascular remodeling by regulating the stability of growth factor receptors, such as PDGF-receptor-beta.
Source : Insect cell
Species : Human
Tag : His/GST
Form : Lyophilized from sterile 20 mM Tris, 500 mM NaCl, pH 7.4, 10% glycerol, 3 mM DTT
Molecular Mass : 100 kDa
Protein length : 1-634
Endotoxin : <1.0 EU/μg of the protein as determined by the LAL method
Purity : ≥85 % as determined by SDS-PAGE
Stability : ≥ 1 year
Storage : Store at -80 centigrade
SDS-PAGE Analysis of PDE1C1 :

Lane 1: MW Markers, Lane 2: PDE1C1, SDS-PAGE Analysis of PDE1C1. This protein has a calculated molecular weight of 100 kDa. It has an apparent molecular weight of approximately 97 kDa by SDS-PAGE under reducing condions.

Gene Name : PDE1C phosphodiesterase 1C [ Homo sapiens (human) ]
Official Symbol : PDE1C
Synonyms : PDE1C; phosphodiesterase 1C; Hcam3; DFNA74; hCam-3; cam-PDE 1C; calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C; 3',5'-cyclic-AMP phosphodiesterase; 3',5'-cyclic-GMP phosphodiesterase; Human 3',5' cyclic nucleotide phosphodiesterase (HSPDE1C1A); phosphodiesterase 1C, calmodulin-dependent 70kDa
Gene ID : 5137
mRNA Refseq : NM_001191056
Protein Refseq : NP_001177985
MIM : 602987
UniProt ID : Q14123

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