Recombinant Human PDGFA Associated Protein 1, His-tagged

• Cat.No.: PDAP1-2770H
• Product Overview: Recombinant human PDAP1 protein, fused to His-tag at C-terminus, was expressed inE.coliand purified by using conventional chromatography techniques.MW = 21.7kDa (189aa).

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Description: PDGFA associated protein 1, also known as PDAP1, enhances PDGFA-stimulated cell growth in fibroblasts, but inhibits the mitogenic effect of PDGFB. And its expression is induced by TNF-alpha, and cells overexpressing PDAP1 show significantly less apoptosis on exposure to TNF-alpha.
• Form: Liquid. 20mM Tris-HCl buffer (pH8.0) containing 20% glycerol, 2mM DTT, 100mM NaCl, 0.1mM PMSF.
• Purity: > 90% by SDS - PAGE.
• Concentration: 1 mg/ml (determined by Bradford assay).
• Sequences Of Amino Acids: MPKGGRKGGH KGRARQYTSP EEIDAQLQAE KQKAREEEEQ KEGGDGAAGD PK K EKK SLDS DESEDEEDDY QQKRKGVEGL IDIENPNRVA QTTKKVTQLD LDGP KELSRR EREEIEKQKA KERYMKMHLA GKTEQAKADL ARLAIIRKQR EEAA RKKEEE RKAKDDATLS GKRMQSLSLN KLEHHHHHH.
• Storage: Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.

Gene Information

• Gene Name: PDAP1 PDGFA associated protein 1 [ Homo sapiens ]
• Synonyms: PDGFA associated protein 1; PAP; PAP1; HASPP28; PDAP1; 28 kDa heat- and acid-stable phosphoprotein; PDGF associated protein; PDGF-associated protein; PDGFA-associated protein 1
• Gene ID: 11333
• mRNA Refseq: NM_014891
• Protein Refseq: NP_055706
• MIM: 607075
• UniProt ID: Q13442
• Chromosome Location: 7q22.1