Recombinant Human PDGFA Protein (Ser87-Thr211), His-tagged


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Recombinant Human PDGFA Protein (Ser87-Thr211), His-tagged

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Cat.No. : PDGFA-563H
Product Overview : Recombinant Human PDGFA Protein (AAA60045.1) (Ser87-Thr211) was produced by Yeast expression system. This protein was expressed with a polyhistidine tag at the N-terminus.
Description : Platelet-derived growth factor alpha (PDGFA) is frequently upregulated in various cancers and thought to function as a key player in the development and progression of tumor growth by regulating aspects of cell proliferation, angiogenesis and metastasis.The human platelet-derived growth factor A chain gene (PDGFA) on chromosome 7p22 encodes an important mitogen. Within PDGFA lies a complex minisatellite structure that results in partial duplications of exon 4 and the IVS4 splice donor site.
Source : Yeast
Species : Human
Tag : His
Predicted N Terminal : His
Form : Lyophilized from sterile 30 % CAN, 0.1 % TFA. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Molecular Mass : The recombinant human PDGFA consists of 140 amino acids and predicts a molecular mass of 16.3 kDa.
Protein length : Ser87-Thr211
Purity : > 95 % as determined by SDS-PAGE.
Stability : Samples are stable for up to twelve months from date of receipt at -70 centigrade.
Storage : Store it under sterile conditions at -20 centigrade to -80 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution : It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 mg/ml. Centrifuge the vial at 4ºC before opening to recover the entire contents.
Shipping : In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature.
Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
Gene Name : PDGFA platelet-derived growth factor alpha polypeptide [ Homo sapiens ]
Official Symbol : PDGFA
Synonyms : PDGFA; PDGF A chain; PDGF A; PDGF1; PDGF-1; PDGF A-chain; PDGF subunit A; PDGF-A;
Gene ID : 5154
mRNA Refseq : NM_002607
Protein Refseq : NP_002598
MIM : 173430
UniProt ID : P04085

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