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Recombinant Human PDGFRB Protein, DDK-tagged

Cat.No. : PDGFRB-149H
Product Overview : Recombinant Human PDGFRB(Met-Leu33-Val532) fused with DDK tag at C-terminal was expressed in Insect cells.
  • Specification
  • Gene Information
  • Related Products
Description : This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. This gene is flanked on chromosome 5 by the genes for granulocyte-macrophage colony-stimulating factor and macrophage-colony stimulating factor receptor; all three genes may be implicated in the 5-q syndrome. A translocation between chromosomes 5 and 12, that fuses this gene to that of the translocation, ETV6, leukemia gene, results in chronic myeloproliferative disorder with eosinophilia.
Source : Insect cells
Species : Human
Tag : DDK
Form : 50mM Tris-HCl, pH8.0, 100mM glycine, 10% glycerol.
Molecular Mass : 56.2 kDa
Protein length : Met-Leu33-Val532
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Storage : Store at -80 centigrade. Avoid repeated freeze-thaw cycles. Stable for at least 3 months from receipt of products under proper storage and handling conditions.
Concentration : >50 ug/mL as determined by microplate BCA method
Gene Name : PDGFRB platelet-derived growth factor receptor, beta polypeptide [ Homo sapiens ]
Official Symbol : PDGFRB
Synonyms : PDGFRB; platelet-derived growth factor receptor, beta polypeptide; PDGFR; platelet-derived growth factor receptor beta; CD140b; JTK12; PDGFR1; PDGFR-beta; PDGF-R-beta; CD140 antigen-like family member B; platelet-derived growth factor receptor 1; beta-type platelet-derived growth factor receptor; CD140B; PDGFR-1;
Gene ID : 5159
mRNA Refseq : NM_002609
Protein Refseq : NP_002600
MIM : 173410
UniProt ID : P09619

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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