Recombinant Human PDZK1 Protein, MYC/DDK-tagged

• Cat.No.: PDZK1-1075H
• Product Overview: Recombinant human PDZK1 protein, fused to MYC/DDK tag at C-terminus, was expressed in HEK293.

Specification

• Species: Human
• Source: HEK293
• Tag: DDK&Myc
• Description: This gene encodes a PDZ domain-containing scaffolding protein. PDZ domain-containing molecules bind to and mediate the subcellular localization of target proteins. The encoded protein mediates the localization of cell surface proteins and plays a critical role in cholesterol metabolism by regulating the HDL receptor, scavenger receptor class B type 1. Single nucleotide polymorphisms in this gene may be associated with metabolic syndrome, and overexpression of this gene may play a role in drug resistance of multiple myeloma. Pseudogenes of this gene are located on the long arm of chromosome 1. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2011]
• Form: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
• Molecular Mass: 56.9 kDa
• Purity: >50 ug/mL as determined by microplate BCA method
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: PDZK1 PDZ domain containing 1 [ Homo sapiens ]
• Official Symbol: PDZK1
• Synonyms: CAP70; CLAMP; NHERF-3; NHERF3; PDZD1
• Gene ID: 5174
• mRNA Refseq: NM_001201325
• Protein Refseq: NP_001188254
• MIM: 603831
• UniProt ID: Q5T2W1