Recombinant Human PEX14 Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: PEX14-3614H
• Product Overview: PEX14 MS Standard C13 and N15-labeled recombinant protein (NP_004556) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: This gene encodes an essential component of the peroxisomal import machinery. The protein is integrated into peroxisome membranes with its C-terminus exposed to the cytosol, and interacts with the cytosolic receptor for proteins containing a PTS1 peroxisomal targeting signal. The protein also functions as a transcriptional corepressor and interacts with a histone deacetylase. A mutation in this gene results in one form of Zellweger syndrome.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 41.2 kDa
• AA Sequence: MASSEQAEQPSQPSSTPGSENVLPR EPLIATAVKFLQNSRVRQSPLATRR AFLKKKGLTDEEIDMAFQQSGTAAD EPSSLGPATQVVPVQPPHLISQPYS PAGSRWRDYGALAIIMAGIAFGFHQ LYKKYLLPLILGGREDRKQLERMEA GLSELSGSVAQTVTQLQTTLASVQE LLIQQQQKIQELAHELAAAKATTST NWILESQNINELKSEINSLKGLLLN RRQFPPSPSAPKIPSWQIPVKSPSP SSPAAVNHHSSSDISPVSNESTSSS PGKEGHSPEGSTVTYHLLGPQEEGE GVVDVKGQVRMEVQGEEEKREDKED EEDEEDDDVSHVDEEDCLGVQREDR RGGDGQINEQVEKLRRPEGASNESE RDTRTRPLEQKLISEEDLAANDILD YKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: PEX14 peroxisomal biogenesis factor 14 [ Homo sapiens (human) ]
• Official Symbol: PEX14
• Synonyms: PEX14; peroxisomal biogenesis factor 14; peroxisomal membrane protein PEX14; peroxin-14; PTS1 receptor docking protein; PTS1 receptor-docking protein; NF-E2 associated polypeptide 2; peroxisomal membrane anchor protein PEX14; peroxisomal membrane anchor protein Pex14p; NAPP2; Pex14p; dJ734G22.2; MGC12767
• Gene ID: 5195
• mRNA Refseq: NM_004565
• Protein Refseq: NP_004556
• MIM: 601791
• UniProt ID: O75381