Recombinant Human PGA3 protein, His-tagged

• Cat.No.: PGA3-361H
• Product Overview: Recombinant Human PGA3 protein was fused to His-tag at C-terminus and expressed in HEK293.

Specification

• Description: This gene encodes a protein precursor of the digestive enzyme pepsin, a member of the peptidase A1 family of endopeptidases. The encoded precursor is secreted by gastric chief cells and undergoes autocatalytic cleavage in acidic conditions to form the active enzyme, which functions in the digestion of dietary proteins. This gene is found in a cluster of related genes on chromosome 11, each of which encodes one of multiple pepsinogens. Pepsinogen levels in serum may serve as a biomarker for atrophic gastritis and gastric cancer.
• Source: HEK293
• Species: Human
• Tag: His
• Form: 1x PBS，pH 7.4. Lyophilized powder.
• Molecular Mass: 41.1 kDa
• AA Sequence: IMYKVPLIRKKSLRRTLSERGLLKD FLKKHNLNPARKYFPQWEAPTLVDE QPLENYLDMEYFGTIGIGTPAQDFT VVFDTGSSNLWVPSVYCSSLACTNH NRFNPEDSSTYQSTSETVSITYGTG SMTGILGYDTVQVGGISDTNQIFGL SETEPGSFLYYAPFDGILGLAYPSI SSSGATPVFDNIWNQGLVSQDLFSV YLSADDQSGSVVIFGGIDSSYYTGS LNWVPVTVEGYWQITVDSITMNGEA IACAEGCQAIVDTGTSLLTGPTSPI ANIQSDIGASENSDGDMVVSCSAIS SLPDIVFTINGVQYPVPPSAYILQS EGSCISGFQGMNLPTESGELWILGD VFIRQYFTVFDRANNQVGLAPVAHH HHHH
• Purity: > 90%, by SDS-PAGE gel stained with R250.
• Applications: Quality control, calibrators.
• Storage: Freeze-dried powder at 4 centigrade for three years, after reconstitution at -20 centigrade for one year.

Gene Information

• Gene Name: PGA3
• Official Symbol: PGA3
• Synonyms: PG I
• Gene ID: 643834
• mRNA Refseq: NM_001079807.4
• Protein Refseq: NP_001073275.1
• MIM: 169710
• UniProt ID: P0DJD8