Recombinant Human PGA3 protein, His-tagged

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Recombinant Human PGA3 protein, His-tagged

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Cat.No. : PGA3-361H
Product Overview : Recombinant Human PGA3 protein was fused to His-tag at C-terminus and expressed in HEK293.
Description : This gene encodes a protein precursor of the digestive enzyme pepsin, a member of the peptidase A1 family of endopeptidases. The encoded precursor is secreted by gastric chief cells and undergoes autocatalytic cleavage in acidic conditions to form the active enzyme, which functions in the digestion of dietary proteins. This gene is found in a cluster of related genes on chromosome 11, each of which encodes one of multiple pepsinogens. Pepsinogen levels in serum may serve as a biomarker for atrophic gastritis and gastric cancer.
Source : HEK293
Species : Human
Tag : His
Form : 1x PBS,pH 7.4. Lyophilized powder.
Molecular Mass : 41.1 kDa
AA Sequence : IMYKVPLIRKKSLRR TLSERGLLKDFLKKH NLNPARKYFPQWEAP TLVDEQPLENYLDME YFGTIGIGTPAQDFT VVFDTGSSNLWVPSV YCSSLACTNHNRFNP EDSSTYQSTSETVSI TYGTGSMTGILGYDT VQVGGISDTNQIFGL SETEPGSFLYYAPFD GILGLAYPSISSSGA TPVFDNIWNQGLVSQ DLFSVYLSADDQSGS VVIFGGIDSSYYTGS LNWVPVTVEGYWQIT VDSITMNGEAIACAE GCQAIVDTGTSLLTG PTSPIANIQSDIGAS ENSDGDMVVSCSAIS SLPDIVFTINGVQYP VPPSAYILQSEGSCI SGFQGMNLPTESGEL WILGDVFIRQYFTVF DRANNQVGLAPVAHH HHHH
Purity : > 90%, by SDS-PAGE gel stained with R250.
Applications : Quality control, calibrators.
Storage : Freeze-dried powder at 4 centigrade for three years, after reconstitution at -20 centigrade for one year.
SDS-PAGE of PGA3-361H :

Lane 1: BSA(1.0μg); Lane 2: PGA3 protein(1.0μg)(Reduced); Lane 3: PGA3 protein(1.0μg)(Non-reduced)

Western blot of PGA3-361H :

Lane 2: PGA3 protein(1.0μg)(Reduced); Lane 3: PGA3 protein(1.0μg)(Non-reduced); Using Anti-His tag antibody.

Gene Name : PGA3
Official Symbol : PGA3
Synonyms : PG I
Gene ID : 643834
mRNA Refseq : NM_001079807.4
Protein Refseq : NP_001073275.1
MIM : 169710
UniProt ID : P0DJD8

Related Gene

PGA3PGA5PGAPGA4

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