| Description : |
6-phosphogluconate dehydrogenase is the second dehydrogenase in the pentose phosphate shunt. Deficiency of this enzyme is generally asymptomatic, and the inheritance of this disorder is autosomal dominant. Hemolysis results from combined deficiency of 6-phosphogluconate dehydrogenase and 6-phosphogluconolactonase suggesting a synergism of the two enzymopathies. Several transcript variants encoding different isoforms have been found for this gene. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
53.1 kDa |
| AA Sequence : |
MAQADIALIGLAVMGQNLILNMNDH GFVVCAFNRTVSKVDDFLANEAKGT KVVGAQSLKEMVSKLKKPRRIILLV KAGQAVDDFIEKLVPLLDTGDIIID GGNSEYRDTTRRCRDLKAKGILFVG SGVSGGEEGARYGPSLMPGGNKEAW PHIKTIFQGIAAKVGTGEPCCDWVG DEGAGHFVKMVHNGIEYGDMQLICE AYHLMKDVLGMAQDEMAQAFEDWNK TELDSFLIEITANILKFQDTDGKHL LPKIRDSAGQKGTGKWTAISALEYG VPVTLIGEAVFARCLSSLKDERIQA SKKLKGPQKFQFDGDKKSFLEDIRK ALYASKIISYAQGFMLLRQAATEFG WTLNYGGIALMWRGGCIIRSVFLGK IKDAFDRNPELQNLLLDDFFKSAVE NCQDSWRRAVSTGVQAGIPMPCFTT ALSFYDGYRHEMLPASLIQAQRDYF GAHTYELLAKPGQFIHTNWTGHGGT VSSSSYNATRTRPLEQKLISEEDLA ANDILDYKDDDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
