Recombinant Human PGK1 Protein, MYC/DDK-tagged

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Recombinant Human PGK1 Protein, MYC/DDK-tagged

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Cat.No. : PGK1-1310H
Product Overview : Recombinant human PGK1 protein, fused to MYC/DDK tag at C-terminus, was expressed in HEK293.
Description : The protein encoded by this gene is a glycolytic enzyme that catalyzes the conversion of 1,3-diphosphoglycerate to 3-phosphoglycerate. The encoded protein may also act as a cofactor for polymerase alpha. Additionally, this protein is secreted by tumor cells where it participates in angiogenesis by functioning to reduce disulfide bonds in the serine protease, plasmin, which consequently leads to the release of the tumor blood vessel inhibitor angiostatin. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. Deficiency of the enzyme is associated with a wide range of clinical phenotypes hemolytic anemia and neurological impairment. Pseudogenes of this gene have been defined on chromosomes 19, 21 and the X chromosome. [provided by RefSeq, Jan 2014].
Source : HEK293
Species : Human
Tag : MYC/DDK
Form : 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
Molecular Mass : 44.4 kDa
Purity : >50 ug/mL as determined by microplate BCA method
Concentration : >50 ug/mL as determined by microplate BCA method
Gene Name : PGK1 phosphoglycerate kinase 1 [ Homo sapiens ]
Official Symbol : PGK1
Synonyms : HEL-S-68p; MIG10; PGKA
Gene ID : 5230
mRNA Refseq : NM_000291
Protein Refseq : NP_000282
MIM : 311800
UniProt ID : P00558
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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