Recombinant Human PI3 protein, His-tagged

• Cat.No.: PI3-01H
• Product Overview: Recombinant Human PI3 protein, fused to His-tag, was expressed in E. coli.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: 23-117aa
• Description: This gene encodes an elastase-specific inhibitor that functions as an antimicrobial peptide against Gram-positive and Gram-negative bacteria, and fungal pathogens. The protein contains a WAP-type four-disulfide core (WFDC) domain, and is thus a member of the WFDC domain family. Most WFDC gene members are localized to chromosome 20q12-q13 in two clusters: centromeric and telomeric. This gene belongs to the centromeric cluster. Expression of this gene is upgulated by bacterial lipopolysaccharides and cytokines.
• Form: Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 10% glycerol, 1mM DTT.
• Molecular Mass: 12 kDa
• AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSAVTGVPV KGQDTVKGRVPFNGQDPVKG QVSVKGQDKV KAQEPVKGPVSTKPGSCPII LIRCAMLNPP NRCLKDTDCPGIKKCCEGSC GMACFVPQ
• Purity: > 80%
• Applications: SDS-PAGE
• Storage: Can be stored at 2 centigrade to 8 centigrade for 1 week. For long term storage, aliquot and store at -20 centigrade to -80 centigrade. Avoid repeated freezing and thawing cycles.
• Concentration: 0.25mg/ml

Gene Information

• Gene Name: PI3 peptidase inhibitor 3 [ Homo sapiens (human) ]
• Official Symbol: PI3
• Synonyms: Elafin preproprotein; Cementoin; ESI; SKALP; WAP3; WFDC14
• Gene ID: 5266
• mRNA Refseq: NM_002638
• Protein Refseq: NP_002629
• MIM: 182257
• UniProt ID: P19957