"PI4K2B" Related Products


Recombinant Human PI4K2B protein, GST-tagged, Active

Cat.No. : PI4K2B-160H
Product Overview : Recombinant Human PI4K2B fused with an N-terminal GST tag was expressed in Insect cells.
Description : PI4K2B is a member of the phosphatidylinositol 4-kinase family (PI4K) that phosphorylate phosphatidylinositol to generate phosphatidylinositol 4-phosphate which are immediate precursor of several important signaling and scaffolding molecules. PI4K2B is primarily a cytosolic PI4K that is recruited to membranes where it stimulates phosphatidylinositol 4,5-bisphosphate syntheses. PI4K2B uses phosphatidylinositol as their primary substrate and has no activity on phosphatidylinositol monophosphates. PI4K2B is a restricted minor histocompatibility antigen in patients that had been successfully treated with donor lymphocyte infusions for relapsed chronic myeloid leukemia after allogeneic stem cell transplantation.
Source : Insect cells
Species : Human
Tag : GST
Form : 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.
Bio-activity : 1850 nmol/min/mg
Molecular Mass : ~84 kDa
Purity : >75%
Applications : Kinase Assay
Stability : 1 year at -70 centigrade from the date of shipment
Storage : Store product at –70 centigrade. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
Concentration : 0.1μg/μl
Figure :

Gene Name : PI4K2B phosphatidylinositol 4-kinase type 2 beta [ Homo sapiens ]
Official Symbol : PI4K2B
Synonyms : PI4K2B; phosphatidylinositol 4-kinase type 2 beta; phosphatidylinositol 4-kinase type 2-beta; FLJ11105; PI4KIIB; PIK42B; PI4KII-BETA; phosphatidylinositol 4-kinase type II-beta; phosphatidylinositol 4-kinase type-II beta;
Gene ID : 55300
mRNA Refseq : NM_018323
Protein Refseq : NP_060793
MIM : 612101
UniProt ID : Q8TCG2
Chromosome Location : 4p15.31
Pathway : 3-phosphoinositide biosynthesis, organism-specific biosystem; 3-phosphoinositide biosynthesis, conserved biosystem; D-myo-inositol (1,4,5)-trisphosphate biosynthesis, organism-specific biosystem; D-myo-inositol (1,4,5)-trisphosphate biosynthesis, conserved biosystem; Inositol phosphate metabolism, organism-specific biosystem; Inositol phosphate metabolism, conserved biosystem; Inositol phosphate metabolism, PI=>
Function : 1-phosphatidylinositol 4-kinase activity; ATP binding; kinase activity; nucleotide binding; transferase activity;

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