| Description : |
This gene is involved in the first step in glycosylphosphatidylinositol (GPI)-anchor biosynthesis. The GPI-anchor is a glycolipid found on many blood cells and serves to anchor proteins to the cell surface. This gene encodes a N-acetylglucosaminyl transferase component that is part of the complex that catalyzes transfer of N-acetylglucosamine (GlcNAc) from UDP-GlcNAc to phosphatidylinositol (PI). Alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
83.9 kDa |
| AA Sequence : |
MVLKAFFPTCCVSTDSGLLVGRWVP EQSSAVVLAVLHFPFIPIQVKQLLA QVRQASQVGVAVLGTWCHCRQEPEE SLGRFLESLGAVFPHEPWLRLCRER GGTFWSCEATHRQAPTAPGAPGEDQ VMLIFYDQRQVLLSQLHLPTVLPDR QAGATTASTGGLAAVFDTVARSEVL FRSDRFDEGPVRLSHWQSEGVEASI LAELARRASGPICLLLASLLSLVSA VSACRVFKLWPLSFLGSKLSTCEQL RHRLEHLTLIFSTRKAENPAQLMRK ANTVASVLLDVALGLMLLSWLHGRS RIGHLADALVPVADHVAEELQHLLQ WLMGAPAGLKMNRALDQVLGRFFLY HIHLWISYIHLMSPFVEHILWHVGL SACLGLTVALSLLSDIIALLTFHIY CFYVYGARLYCLKIHGLSSLWRLFR GKKWNVLRQRVDSCSYDLDQLFIGT LLFTILLFLLPTTALYYLVFTLLRL LVVAVQGLIHLLVDLINSLPLYSLG LRLCRPYRLADKPTALQPRGAHLPP PQLWLPPQALLGRPVPQAVPWGAHL PLEAERGQAGLRELLARLAPPHGHS QPSALPGWHQLSWRMSCALWTLLCA PEHGRPCYHTLGLEVIGSEQMWGWP ARLAALHHWHCLPWDPLPTCCGHHG GEHSNPRCPEHCPMPTLCTQVQRVR PPQQPQVEGWSPWGLPSGSALAVGV EGPCQDEPPSPRHPLAPSAEQHPAS GGLKQSLTPVPSGPGPSLPEPHGVY LRMFPGEVALTRTRPLEQKLISEED LAANDILDYKDDDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
