"PIK3CA" Related Products

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Recombinant Human PIK3CA protein, Flag-tagged, Biotinylated

Cat.No.: PIK3CA-70H
Product Overview: Recombinant Human PIK3CA[1-1068(end) amino acids of accession number NP_006209.2] was coexpressed as N-terminal DYKDDDDK tagged, biotinylated protein (128 kDa) with PIK3R1[1-724(end) amino acids of accession number NP_852664.1] in insect cell and biotinyl
Source: Insect cell
Species: Human
Tag: Flag
Form: 50 mM Tris-HCl, 150 mM NaCl, 0.05% Brij35, 1 mM DTT, 10% glycerol, pH7.5
Molecular Mass: 128 kDa
Purity: >90% as determined by SDS-PAGE and CBB staining
Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
Gene Name: PIK3CA phosphoinositide-3-kinase, catalytic, alpha polypeptide [ Homo sapiens ]
Official Symbol: PIK3CA
Synonyms: PIK3CA; PI3K; PI3K-alpha; PI3-kinase p110 subunit alpha; ptdIns-3-kinase subunit p110-alpha; serine/threonine protein kinase PIK3CA; p110-alpha; MGC142161; MGC142163;
Gene ID: 5290
mRNA Refseq: NM_006218
Protein Refseq: NP_006209
MIM: 171834
UniProt ID: P42336
Chromosome Location: 3q26.3
Pathway: 3-phosphoinositide biosynthesis, organism-specific biosystem; 3-phosphoinositide biosynthesis, conserved biosystem; Acute myeloid leukemia, organism-specific biosystem; Acute myeloid leukemia, conserved biosystem; Adaptive Immune System, organism-specific biosystem; Aldosterone-regulated sodium reabsorption, organism-specific biosystem; Aldosterone-regulated sodium reabsorption, conserved biosystem;
Function: 1-phosphatidylinositol-3-kinase activity; ATP binding; insulin receptor substrate binding; nucleotide binding; phosphatidylinositol 3-kinase activity; phosphatidylinositol-4,5-bisphosphate 3-kinase activity; phosphotransferase activity, alcohol group as acceptor; protein binding; protein kinase activator activity; protein serine/threonine kinase activity;

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Optional requirements on this protein    +Expand
C-fusion    N-fusion   Non-tagged
His    GST   Fc   Others
<1.0 eu/μg    <0.1 eu/μg   <0.01 eu/μg   Not required
Monomer Isolation    Dimer Isolation    Not required
>80% by SDS-PAGE    >90% by SDS-PAGE   >95% by SDS-PAGE   Others

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