Recombinant Human PIK3R5 Protein (1-494 aa), His-SUMO-tagged

• Cat.No.: PIK3R5-1084H
• Product Overview: Recombinant Human PIK3R5 Protein (1-494 aa) is produced by E. coli expression system. This protein is fused with a 6xHis-SUMO tag at the N-terminal. Research Area: Signal Transduction. Protein Description: Full Length of Isoform 2.

Specification

• Description: Regulatory subunit of the PI3K gamma complex. Required for recruitment of the catalytic subunit to the plasma mbrane via interaction with beta-gamma G protein dimers. Required for G protein-mediated activation of PIK3CG.
• Source: E. coli
• Species: Human
• Tag: His-SUMO
• Form: Tris-based buffer, 50% glycerol
• Molecular Mass: 70.9 kDa
• Protein length: 1-494 aa
• AA Sequence: MDSGYVEDSEESSSEWPWRRGSQER RGHRRPGQKFIRIYKLFKSTSQLVL RRDSRSLEGSSDTALPLRRAGSLCS PLDEPVSPPSRAQRSRSLPQPKLGT QLPSWLLAPASRPQRRRPFLSGDED PKASTLRVVVFGSDRISGKVARAYS NLRRLENNRPLLTRFFKLQFFYVPV KRSHGTSPGACPPPRSQTPSPPTDS PRHASPGELGTTPWEESTNDISHYL GMLDPWYERNVLGLMHLPPEVLCQQ SLKAEAQALEGSPTQLPILADMLLY YCRFAARPVLLQVYQTELTFITGEK TTEIFIHSLELGHSAATRAIKASGP GSKRLGIDGDREAVPLTLQIIYSKG AISGRSRWSNLEKVCTSVNLNKACR KQEELDSSMEALTLNLTEVVKRQNS KSKKGFNQISTSQIKVDKVQIIGSN SCPFAVCLDQDERKILQSVVRCEVS PCYKPEKSDLSSPPQTPPDLPAQAA PDLCSLLCLPIMTFSGALP
• Purity: > 90% as determined by SDS-PAGE.
• Notes: Repeated freezing and thawing is not recommended. Store working aliquots at 4 centigrade for up to one week.
• Storage: The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20 centigrade/-80 centigrade. The shelf life of lyophilized form is 12 months at -20 centigrade/-80 centigrade.
• Concentration: A hardcopy of COA with concentration instruction is sent along with the products.

Gene Information

• Gene Name: PIK3R5 phosphoinositide-3-kinase, regulatory subunit 5 [ Homo sapiens ]
• Official Symbol: PIK3R5
• Synonyms: PIK3R5; p101; P101 PI3K; FOAP-2; P101-PI3K; F730038I15Rik; FLJ26116
• Gene ID: 23533
• mRNA Refseq: NM_001142633
• Protein Refseq: NP_001136105
• MIM: 611317
• UniProt ID: Q8WYR1