Recombinant Human PINK1 Protein, GST-tagged PINK1-392H

Recombinant Human PINK1 Protein, GST-tagged

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Recombinant Human PINK1 Protein, GST-tagged

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Cat.No. : PINK1-392H
Product Overview : Recombinant human PINK1 (114-end) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.
Description : PTEN-induced kinase 1 (PINK1) is a serine/threonine protein kinase that was identified initially in cancer cells as a gene up-regulated by overexpression of the major tumor suppressor, PTEN. It localizes to mitochondria, and regulates multiple aspects of mitochondrial biology. It is implicated in ubiquitin-dependent protein catabolic process to clear damaged mitochondria through selective autophagy (mitophagy). Mutations in the PINK1 gene are linked to early-onset recessive Parkinson disease.
Source : Insect cell
Species : Human
Tag : GST
Form : Liquid
Molecular Mass : 78 kDa
Purity : >70%
Storage : Store product at -70 centigrade. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
Storage Buffer : 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.
Gene Name : PINK1 PTEN induced putative kinase 1 [ Homo sapiens ]
Official Symbol : PINK1
Synonyms : PINK1; PTEN induced putative kinase 1; PARK6, Parkinson disease (autosomal recessive) 6; serine/threonine-protein kinase PINK1, mitochondrial; protein kinase BRPK; PTEN-induced putative kinase protein 1; BRPK; PARK6; FLJ27236;
Gene ID : 65018
mRNA Refseq : NM_032409
Protein Refseq : NP_115785
MIM : 608309
UniProt ID : Q9BXM7

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