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- Human(7)
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- P. humanus(1)
- T. castaneum(1)
- Zebrafish(1)
Recombinant Human PINK1 Protein, GST-tagged
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| Cat.No. : | PINK1-392H |
| Product Overview : | Recombinant human PINK1 (114-end) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag. |
| Description : | PTEN-induced kinase 1 (PINK1) is a serine/threonine protein kinase that was identified initially in cancer cells as a gene up-regulated by overexpression of the major tumor suppressor, PTEN. It localizes to mitochondria, and regulates multiple aspects of mitochondrial biology. It is implicated in ubiquitin-dependent protein catabolic process to clear damaged mitochondria through selective autophagy (mitophagy). Mutations in the PINK1 gene are linked to early-onset recessive Parkinson disease. |
| Source : | Insect cell |
| Species : | Human |
| Tag : | GST |
| Form : | Liquid |
| Molecular Mass : | 78 kDa |
| Purity : | >70% |
| Storage : | Store product at -70 centigrade. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles. |
| Storage Buffer : | 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol. |
| Gene Name : | PINK1 PTEN induced putative kinase 1 [ Homo sapiens ] |
| Official Symbol : | PINK1 |
| Synonyms : | PINK1; PTEN induced putative kinase 1; PARK6, Parkinson disease (autosomal recessive) 6; serine/threonine-protein kinase PINK1, mitochondrial; protein kinase BRPK; PTEN-induced putative kinase protein 1; BRPK; PARK6; FLJ27236; |
| Gene ID : | 65018 |
| mRNA Refseq : | NM_032409 |
| Protein Refseq : | NP_115785 |
| MIM : | 608309 |
| UniProt ID : | Q9BXM7 |
◆ Recombinant Protein
| PINK1-3902H | Recombinant Human PINK1 Protein, GST-tagged | +Inquiry |
| PINK1-002P | Recombinant P. humanus PINK1 Protein | +Inquiry |
| PINK1-357H | Recombinant Human PTEN Protein, His-tagged | +Inquiry |
| PINK1-001T | Recombinant T. castaneum PINK1 Protein, MBP/His-tagged | +Inquiry |
| PINK1-30963TH | Recombinant Human PINK1 | +Inquiry |
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◆ Lysates
| PINK1-3929HCL | Recombinant Human PINK1 Cell Lysate | +Inquiry |
| PINK1-1352HCL | Recombinant Human PINK1 cell lysate | +Inquiry |
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