Recombinant Human PIP4K2C Protein (A2-A421), His tagged

• Cat.No.: PIP4K2C-0813H
• Product Overview: Recombinant Human 6His-TEV-GG-PIP4K2C(A2-A421 end) Protein was expressed in E. coli.

Specification

• Description: Phosphatidylinositol 5-phosphate 4-kinase with low enzymatic activity. May be a GTP sensor, has higher GTP-dependent kinase activity than ATP-dependent kinase activity. PIP4Ks negatively regulate insulin signaling through a catalytic-independent mechanism. They interact with PIP5Ks and suppress PIP5K-mediated PtdIns(4,5)P2 synthesis and insulin-dependent conversion to PtdIns(3,4,5)P3.
• Source: E. coli
• Species: Human
• Tag: His
• Form: Liquid
• Protein Length: A2-A421
• Endotoxin: < 0.01 EU per μg of the protein
• Purity: 90%
• Stability: Samples are stable for up to twelve months from date of receipt at -20 to -80 centigrade.
• Storage: Store it under sterile conditions at -20 to -80 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
• Storage Buffer: Supplied as sterile 50 mM Tris-HCl (pH7.5), 200 mM NaCl, 20% glycerol
• Shipping: It is shipped out with blue ice.

Gene Information

• Gene Name: PIP4K2C phosphatidylinositol-5-phosphate 4-kinase, type II, gamma [ Homo sapiens (human) ]
• Official Symbol: PIP4K2C
• Synonyms: PIP4K2C; phosphatidylinositol-5-phosphate 4-kinase, type II, gamma; phosphatidylinositol 4 phosphate 5 kinase, type II, gamma, PIP5K2C; phosphatidylinositol-5-phosphate 4-kinase type-2 gamma; FLJ22055; PIP4KII-gamma; PI(5)P 4-kinase type II gamma; phosphatidylinositol 4-phosphate 5-kinase; phosphatidylinositol-4-phosphate 5-kinase, type II, gamma; PIP5K2C
• Gene ID: 79837
• mRNA Refseq: NM_001146258
• Protein Refseq: NP_001139730
• UniProt ID: Q8TBX8