Recombinant Human PKD2
Cat.No. : | PKD2-30689TH |
Product Overview : | Recombinant fragment of Human Polycystin 2 with N terminal proprietary tag; predicted MWt: 36.63 kDa including the tag. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes a member of the polycystin protein family. The encoded protein is a multi-pass membrane protein that functions as a calcium permeable cation channel, and is involved in calcium transport and calcium signaling in renal epithelial cells. This protein interacts with polycystin 1, and they may be partners in a common signaling cascade involved in tubular morphogenesis. Mutations in this gene are associated with autosomal dominant polycystic kidney disease type 2. |
Protein length : | 100 amino acids |
Molecular Weight : | 36.630kDa inclusive of tags |
Source : | Wheat germ |
Tissue specificity : | Strongly expressed in ovary, fetal and adult kidney, testis, and small intestine. Not detected in peripheral leukocytes. |
Form : | Liquid |
Purity : | Proprietary Purification |
Storage buffer : | pH: 8.00Constituents:0.79% Tris HCl, 0.3% Glutathione |
Storage : | Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles. |
Sequences of amino acids : | PVSKTEKTNFKTLSSMEDFWKFTEG SLLDGLYWKMQPSNQTEADNRSFIF YENLLLGVPRIRQLRVRNGSCSIPQ DLRDEIKECYDVYSVSSEDRAPFGP |
Sequence Similarities : | Belongs to the polycystin family.Contains 1 EF-hand domain. |
Gene Name : | PKD2 polycystic kidney disease 2 (autosomal dominant) [ Homo sapiens ] |
Official Symbol : | PKD2 |
Synonyms : | PKD2; polycystic kidney disease 2 (autosomal dominant); polycystin-2; Pc 2; PC2; PKD4; transient receptor potential cation channel; subfamily P; member 2; TRPP2; |
Gene ID : | 5311 |
mRNA Refseq : | NM_000297 |
Protein Refseq : | NP_000288 |
MIM : | 173910 |
Uniprot ID : | Q13563 |
Chromosome Location : | 4q22.1 |
Function : | ATPase binding; calcium ion binding; channel activity; cytoskeletal protein binding; ion channel activity; |
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Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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