Active Recombinant Full Length Human PRKD2 Protein, GST tagged

• Cat.No.: PKD2-410H
• Product Overview: Recombinant full length human PKD2 (PRKD2) was expressed by baculovirus in Sf9 insect cells using a N-terminal GST tag.

Specification

• Species: Human
• Source: Insect Cells
• Tag: GST
• Protein Length: 1-878 aa
• Description: The protein encoded by this gene belongs to the protein kinase D (PKD) family of serine/threonine protein kinases. This kinase can be activated by phorbol esters as well as by gastrin via the cholecystokinin B receptor (CCKBR) in gastric cancer cells. It can bind to diacylglycerol (DAG) in the trans-Golgi network (TGN) and may regulate basolateral membrane protein exit from TGN. Alternative splicing results in multiple transcript variants encoding different isoforms.
• Form: In 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.
• Bio-activity: Specific Activity 224 nmol/min/mg
• Purity: >80%
• Storage: Store product at –70 centigrade. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
• Concentration: 0.1 μg/μL

Gene Information

• Gene Name: PRKD2 protein kinase D2 [ Homo sapiens (human) ]
• Official Symbol: PRKD2
• Synonyms: PRKD2; protein kinase D2; serine/threonine-protein kinase D2; DKFZP586E0820; HSPC187; PKD2; nPKC-D2
• Gene ID: 25865
• mRNA Refseq: NM_016457
• Protein Refseq: NP_057541
• MIM: 607074
• UniProt ID: Q9BZL6