| Description : |
The protein encoded by this gene belongs to the protein kinase D (PKD) family of serine/threonine protein kinases. This kinase can be activated by phorbol esters as well as by gastrin via the cholecystokinin B receptor (CCKBR) in gastric cancer cells. It can bind to diacylglycerol (DAG) in the trans-Golgi network (TGN) and may regulate basolateral membrane protein exit from TGN. Alternative splicing results in multiple transcript variants encoding different isoforms. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
96.5 kDa |
| AA Sequence : |
MATAPSYPAGLPGSPGPGSPPPPGG LELQSPPPLLPQIPAPGSGVSFHIQ IGLTREFVLLPAASELAHVKQLACS IVDQKFPECGFYGLYDKILLFKHDP TSANLLQLVRSSGDIQEGDLVEVVL SASATFEDFQIRPHALTVHSYRAPA FCDHCGEMLFGLVRQGLKCDGCGLN YHKRCAFSIPNNCSGARKRRLSSTS LASGHSVRLGTSESLPCTAEELSRS TTELLPRRPPSSSSSSSASSYTGRP IELDKMLLSKVKVPHTFLIHSYTRP TVCQACKKLLKGLFRQGLQCKDCKF NCHKRCATRVPNDCLGEALINGDVP MEEATDFSEADKSALMDESEDSGVI PGSHSENALHASEEEEGEGGKAQSS LGYIPLMRVVQSVRHTTRKSSTTLR EGWVVHYSNKDTLRKRHYWRLDCKC ITLFQNNTTNRYYKEIPLSEILTVE SAQNFSLVPPGTNPHCFEIVTANAT YFVGEMPGGTPGGPSGQGAEAARGW ETAIRQALMPVILQDAPSAPGHAPH RQASLSISVSNSQIQENVDIATVYQ IFPDEVLGSGQFGVVYGGKHRKTGR DVAVKVIDKLRFPTKQESQLRNEVA ILQSLRHPGIVNLECMFETPEKVFV VMEKLHGDMLEMILSSEKGRLPERL TKFLITQILVALRHLHFKNIVHCDL KPENVLLASADPFPQVKLCDFGFAR IIGEKSFRRSVVGTPAYLAPEVLLN QGYNRSLDMWSVGVIMYVSLSGTFP FNEDEDINDQIQNAAFMYPASPWSH ISAGAIDLINNLLQVKMRKRYSVDK SLSHPWLQEYQTWLDLRELEGKMGE RYITHESDDARWEQFAAEHPLPGSG LPTDRDLGGACPPQDHDMQGLAERI SVLTRTRPLEQKLISEEDLAANDIL DYKDDDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
