| Description : |
This gene encodes a member of the arm-repeat (armadillo) and plakophilin gene families. Plakophilin proteins contain numerous armadillo repeats, localize to cell desmosomes and nuclei, and participate in linking cadherins to intermediate filaments in the cytoskeleton. This protein may act in cellular desmosome-dependent adhesion and signaling pathways. Two transcript variants encoding different isoforms have been found for this gene. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
86.9 kDa |
| AA Sequence : |
MQDGNFLLSALQPEAGVCSLALPSD LQLDRRGAEGPEAERLRAARVQEQV RARLLQLGQQPRHNGAAEPEPEAET ARGTSRGQYHTLQAGFSSRSQGLSG DKTSGFRPIAKPAYSPASWSSRSAV DLSCSRRLSSAHNGGSAFGAAGYGG AQPTPPMPTRPVSFHERGGVGSRAD YDTLSLRSLRLGPGGLDDRYSLVSE QLEPAATSTYRAFAYERQASSSSSR AGGLDWPEATEVSPSRTIRAPAVRT LQRFQSSHRSRGVGGAVPGAVLEPV ARAPSVRSLSLSLADSGHLPDVHGF NSYGSHRTLQRLSSGFDDIDLPSAV KYLMASDPNLQVLGAAYIQHKCYSD AAAKKQARSLQAVPRLVKLFNHANQ EVQRHATGAMRNLIYDNADNKLALV EENGIFELLRTLREQDDELRKNVTG ILWNLSSSDHLKDRLARDTLEQLTD LVLSPLSGAGGPPLIQQNASEAEIF YNATGFLRNLSSASQATRQKMRECH GLVDALVTSINHALDAGKCEDKSVE NAVCVLRNLSYRLYDEMPPSALQRL EGRGRRDLAGAPPGEVVGCFTPQSR RLRELPLAADALTFAEVSKDPKGLE WLWSPQIVGLYNRLLQRCELNRHTT EAAAGALQNITAGDRRWAGVLSRLA LEQERILNPLLDRVRTADHHQLRSL TGLIRNLSRNARNKDEMSTKVVSHL IEKLPGSVGEKSPPAEVLVNIIAVL NNLVVASPIAARDLLYFDGLRKLIF IKKKRDSPDSEKSSRAASSLLANLW QYNKLHRDFRAKGYRKEDFLGPTRT RPLEQKLISEEDLAANDILDYKDDD DKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
