Recombinant Human PLAGL1 Protein, HIS-tagged

• Cat.No.: PLAGL1-069H
• Product Overview: Recombinant Human CDH6 fused with His tag at N-termina was expressed in E. coli.

Specification

• Description: This gene encodes a C2H2 zinc finger protein that functions as a suppressor of cell growth. This gene is often deleted or methylated and silenced in cancer cells. In addition, overexpression of this gene during fetal development is thought to be the causal factor for transient neonatal diabetes mellitus (TNDM). Alternative splicing and the use of alternative promoters results in multiple transcript variants encoding two different protein isoforms. The P1 downstream promoter of this gene is imprinted, with preferential expression from the paternal allele in many tissues.
• Source: E. coli
• Tag: HIS
• Form: 50mM Tris, pH 8.0, 500mM NaCl, 10% glycerol.
• Molecular Mass: 44.5 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: PLAGL1 pleiomorphic adenoma gene-like 1 [ Homo sapiens ]
• Official Symbol: PLAGL1
• Synonyms: PLAGL1; pleiomorphic adenoma gene-like 1; zinc finger protein PLAGL1; LOT1; ZAC; LOT-1; PLAG-like 1; ZAC tumor supressor; tumor supressor ZAC; lost on transformation 1; pleiomorphic adenoma-like protein 1; pleiomorphic adenoma gene-like protein 1; ZAC1; MGC126275; MGC126276; DKFZp781P1017
• Gene ID: 5325
• mRNA Refseq: NM_001080951
• Protein Refseq: NP_001074420
• MIM: 603044
• UniProt ID: Q9UM63