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Recombinant Human PLAT Protein, His-tagged

Cat.No. : PLAT-051H
Product Overview : Purified recombinant protein of Human plasminogen activator, tissue (PLAT), transcript variant 3, was expressed in HEK293 cells.
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Description : Converts the abundant, but inactive, zymogen plasminogen to plasmin by hydrolyzing a single Arg-Val bond in plasminogen. By controlling plasmin-mediated proteolysis, it plays an important role in tissue remodeling and degradation, in cell migration and many other physiopathological events. Plays a direct role in facilitating neuronal migration.
Source : HEK293 cell
Species : Human
Tag : His
Molecular Mass : 60 kDa
AA Sequence : SYQVICRDEKTQMIYQQHQSWLRPV LRSNRVEYCWCNSGRAQCHSVPVKS CSEPRCFNGGTCQQALYFSDFVCQC PEGFAGKCCEIDTRATCYEDQGISY RGTWSTAESGAECTNWNSSALAQKP YSGRRPDAIRLGLGNHNYCRNPDRD SKPWCYVFKAGKYSSEFCSTPACSE GNSDCYFGNGSAYRGTHSLTESGAS CLPWNSMILIGKVYTAQNPSAQALG LGKHNYCRNPDGDAKPWCHVLKNRR LTWEYCDVPSCSTCGLRQYSQPQFR IKGGLFADIASHPWQAAIFAKHRRS PGERFLCGGILISSCWILSAAHCFQ ERFPPHHLTVILGRTYRVVPGEEEQ KFEVEKYIVHKEFDDDTYDNDIALL QLKSDSSRCAQESSVVRTVCLPPAD LQLPDWTECELSGYGKHEALSPFYS ERLKEAHVRLYPSSRCTSQHLLNRT VTDNMLCAGDTRSGGPQANLHDACQ GDSGGPLVCLNDGRMTLVGIISWGL GCGQKDVPGVYTKVTNYLDWIRDNM RPVDHHHHHH
Purity : > 95% as determined by SDS-PAGE and Coomassie blue staining
Storage Buffer : Supplied as a 0.2 µm filtered solution of 20mM MES, 150mM NaCl, 0.2mM GaCl2, 30% glycerol, pH 5.5
Gene Name : PLAT plasminogen activator, tissue [ Homo sapiens ]
Official Symbol : PLAT
Synonyms : PLAT; plasminogen activator, tissue; tissue-type plasminogen activator; alteplase; reteplase; t-plasminogen activator; plasminogen activator, tissue type; tissue plasminogen activator (t-PA); TPA; T-PA; DKFZp686I03148;
Gene ID : 5327
mRNA Refseq : NM_000930
Protein Refseq : NP_000921
MIM : 173370
UniProt ID : P00750

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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