Recombinant Human PLCD3 Protein (Leu528-Ser789), N-His tagged

• Cat.No.: PLCD3-3975H
• Product Overview: Recombinant human PLCD3 (Leu528-Ser789) fused with the N-His tag was expressed in E. coli.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: Leu528-Ser789
• Description: This gene encodes a member of the phospholipase C family, which catalyze the hydrolysis of phosphatidylinositol 4,5-bisphosphate to generate the second messengers diacylglycerol and inositol 1,4,5-trisphosphate (IP3) . Diacylglycerol and IP3 mediate a variety of cellular responses to extracellular stimuli by inducing protein kinase C and increasing cytosolic Ca (2+) concentrations. This enzyme localizes to the plasma membrane and requires calcium for activation. Its activity is inhibited by spermine, sphingosine, and several phospholipids.
• Form: Lyophilized powder/frozen liquid
• Molecular Mass: 31.62 kDa
• Purity: >90% as determined by SDS-PAGE.
• Notes: For research use only.
• Storage: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8 centigrade for one week. Store at -20 to -80 centigrade for twelve months from the date of receipt.
• Storage Buffer: 0.01M PBS, pH 7.4, 0.02% NLS
• Reconstitution: Reconstitute in sterile water for a stock solution.
• Shipping: They are shipped out with dry ice/blue ice unless customers require otherwise.

Gene Information

• Gene Name: PLCD3 phospholipase C, delta 3 [ Homo sapiens (human) ]
• Official Symbol: PLCD3
• Synonyms: PLCD3; phospholipase C delta 3; PLC-delta-3; 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-3; 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase delta-3; PLC delta3; phosphoinositide phospholipase C-delta-3; EC 3.1.4.11
• Gene ID: 113026
• mRNA Refseq: NM_133373
• Protein Refseq: NP_588614
• MIM: 608795
• UniProt ID: Q8N3E9