Recombinant Human PLIN3 Protein, His-tagged

• Cat.No.: PLIN3-2597H
• Product Overview: Recombinant Human PLIN3 Protein (Glu134-Lys434) with a N-His tag was expressed in E. coli.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: Glu134-Lys434
• Description: Mannose 6-phophate receptors (MPRs) deliver lysosomal hydrolase from the Golgi to endosomes and then return to the Golgi complex. The protein encoded by this gene interacts with the cytoplasmic domains of both cation-independent and cation-dependent MPRs, and is required for endosome-to-Golgi transport. This protein also binds directly to the GTPase RAB9 (RAB9A), a member of the RAS oncogene family. The interaction with RAB9 has been shown to increase the affinity of this protein for its cargo. Multiple transcript variants encoding different isoforms have been found for this gene.
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 33.2 kDa
  Accurate Molecular Mass: 37 kDa
• Endotoxin: <1.0 EU per 1µg (determined by the LAL method).
• Purity: > 97%
• Applications: Positive Control; Immunogen; SDS-PAGE; WB.
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
• Storage Buffer: PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
• Reconstitution: Reconstitute in PBS or others.

Gene Information

• Gene Name: PLIN3 perilipin 3 [ Homo sapiens (human) ]
• Official Symbol: PLIN3
• Synonyms: PLIN3; perilipin 3; M6PRBP1, mannose 6 phosphate receptor binding protein 1; perilipin-3; cargo selection protein (mannose 6 phosphate receptor binding protein); MPR BINDING PROTEIN; 47 KD; placental protein 17; PP17; TIP47; 47 kDa MPR-binding protein; cargo selection protein TIP47; tail-interacting protein, 47 kD; mannose-6-phosphate receptor-binding protein 1; M6PRBP1; MGC2012; MGC11117
• Gene ID: 10226
• mRNA Refseq: NM_001164189
• Protein Refseq: NP_001157661
• MIM: 602702
• UniProt ID: O60664