| Description : |
Coreceptor for SA3A. Necessary for signaling by class 3 saphorins and subsequent rodeling of the cytoskeleton. Plays a role in axon guidance in the developing nervous syst. Class 3 saphorins bind to a complex composed of a neuropilin and a plexin. The plexin modulates the affinity of the complex for specific saphorins, and its Cytoplasmic domain is required for the activation of down-stream signaling events in the cytoplasm. |
| Source : |
E. coli |
| Species : |
Human |
| Tag : |
His |
| Form : |
Tris-based buffer, 50% glycerol |
| Molecular Mass : |
60.0 kDa |
| Protein length : |
25-521 aa |
| AA Sequence : |
LLTRQPAPLSQKQRSFVTFRGEPAE GFNHLVVDERTGHIYLGAVNRIYKL SSDLKVLVTHETGPDEDNPKCYPPR IVQTCNEPLTTTNNVNKMLLIDYKE NRLIACGSLYQGICKLLRLEDLFKL GEPYHKKEHYLSGVNESGSVFGVIV SYSNLDDKLFIATAVDGKPEYFPTI SSRKLTKNSEADGMFAYVFHDEFVA SMIKIPSDTFTIIPDFDIYYVYGFS SGNFVYFLTLQPEMVSPPGSTTKEQ VYTSKLVRLCKEDTAFNSYVEVPIG CERSGVEYRLLQAAYLSKAGAVLGR TLGVHPDDDLLFTVFSKGQKRKMKS LDESALCIFILKQINDRIKERLQSC YRGEGTLDLAWLKVKDIPCSSALLT IDDNFCGLDMNAPLGVSDMVRGIPV FTEDRDRMTSVIAYVYKNHSLAFVG TKSGKLKKSFGTGPQGGITQEWIGV AGDPPGANIASQEQMLCVYLQCSSH KAISDQRVQPLLCCFLNVPGNS |
| Purity : |
> 90% as determined by SDS-PAGE. |
| Notes : |
Repeated freezing and thawing is not recommended. Store working aliquots at 4 centigrade for up to one week. |
| Storage : |
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20 centigrade/-80 centigrade. The shelf life of lyophilized form is 12 months at -20 centigrade/-80 centigrade. |
| Concentration : |
A hardcopy of COA with concentration instruction is sent along with the products. |
