Recombinant Human PML protein, MYC/DDK-tagged

• Cat.No.: PML-17H
• Product Overview: Recombinant Human PML, transcript variant 5, fused with MYC/DDK tag at C-terminal was expressed in HEK293.

Specification

• Species: Human
• Source: HEK293
• Tag: DDK&Myc
• Form: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 61.8 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: PML promyelocytic leukemia [ Homo sapiens ]
• Official Symbol: PML
• Synonyms: PML; promyelocytic leukemia; protein PML; MYL; RNF71; TRIM19; RING finger protein 71; promyelocytic leukemia protein; tripartite motif protein TRIM19; probable transcription factor PML; promyelocytic leukemia, inducer of; tripartite motif-containing protein 19; PP8675
• Gene ID: 5371
• mRNA Refseq: NM_033244
• Protein Refseq: NP_150247
• MIM: 102578
• UniProt ID: P29590
• Chromosome Location: 15q24.1
• Pathway: Acute myeloid leukemia, organism-specific biosystem; Acute myeloid leukemia, conserved biosystem; Cytokine Signaling in Immune system, organism-specific biosystem; Direct p53 effectors, organism-specific biosystem; Endocytosis, organism-specific biosystem; Endocytosis, conserved biosystem; Herpes simplex infection, organism-specific biosystem
• Function: DNA binding; SMAD binding; SUMO binding; cobalt ion binding; metal ion binding; protein binding; protein heterodimerization activity; protein homodimerization activity; transcription coactivator activity; ubiquitin protein ligase binding; zinc ion binding; zinc ion binding