Recombinant Human PNPLA2 protein, MYC/DDK-tagged

• Cat.No.: PNPLA2-320H
• Product Overview: Recombinant Human PNPLA2 fused with MYC/DDK tag at C-terminal was expressed in HEK293.

Specification

• Species: Human
• Source: HEK293
• Tag: DDK&Myc
• Description: This gene encodes an enzyme which catalyzes the first step in the hydrolysis of triglycerides in adipose tissue. Mutations in this gene are associated with neutral lipid storage disease with myopathy.
• Form: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 55.1 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Notes: Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps.
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: PNPLA2 patatin-like phospholipase domain containing 2 [ Homo sapiens ]
• Official Symbol: PNPLA2
• Synonyms: PNPLA2; patatin-like phospholipase domain containing 2; patatin-like phospholipase domain-containing protein 2; ATGL; desnutrin; FP17548; TTS 2.2; TTS2.2; IPLA2-zeta; triglyceride hydrolase; adipose triglyceride lipase; transport-secretion protein 2.2; pigment epithelium-derived factor; calcium-independent phospholipase A2; TTS2; PEDF-R; TTS-2.2; 1110001C14Rik; DKFZp667M109
• Gene ID: 57104
• mRNA Refseq: NM_020376
• Protein Refseq: NP_065109
• MIM: 609059
• UniProt ID: Q96AD5
• Chromosome Location: 11p15.5
• Pathway: Fatty Acid Beta Oxidation, organism-specific biosystem; Triacylglyceride Synthesis, organism-specific biosystem; triacylglycerol degradation, organism-specific biosystem
• Function: hydrolase activity; retinyl-palmitate esterase activity; triglyceride lipase activity