Recombinant Human Podoplanin, His-tagged

• Cat.No.: PDPN-379H
• Product Overview: Recombinant human PDPN protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by conventional chromatography techniques, 13.4 kDa (130 aa).

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Description: Podoplanin(PDPN) is a small mucin-like transmembrane protein, widely expressed in various specialized cell types throughout the body. This is a type-I integral membrane glycoprotein with diverse distribution in human tissues. The physiological function of this protein may be related to its mucin-type character. The homologous protein in other species has been described as a differentiation antigen and influenza-virus receptor.
• Sequences of amino acids: MGSSHHHHHH SSGLVPRGSH MASTGQPEDD TETTGLEGGV AMPGAEDDVV TPGTSEDRYK SGLTTLVATS VNSVTGIRIE DLPTSESTVH AQEQSPSATA SNVATSHSTE KVDGDTQTTV EKDGLSTVTL
• Formulation: Liquid. In 20 mM Tris-HCl buffer (pH 7.5) containing 100 mM NaCl
• Purity: > 95% by SDS - PAGE
• Concentration: 1 mg/ml (determined by Bradford assay)
• Storage: Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.

Gene Information

• Gene Name: PDPN podoplanin [ Homo sapiens ]
• Synonyms: PDPN; podoplanin; T1A; GP36; GP40; Gp38; OTS8; T1A-2; AGGRUS; HT1A-1; PA2.26; lung type-I cell membrane-associated glycoprotein; hT1alpha-1; hT1alpha-2; OTTHUMP00000009640; OTTHUMP00000044504; glycoprotein, 36-KD; lung type I cell membrane associated glycoprotein; lung type-I cell membrane-associated glycoprotein (T1A-2); aggrus; PA2.26; Glycoprotein 36; PA2.26 antigen; T1-alpha; Aggrus; T1-alpha; lung type-I cell membrane-associated glycoprotein
• Gene ID: 10630
• mRNA Refseq: NM_001006624
• Protein Refseq: NP_001006625
• MIM: 608863
• UniProt ID: Q86YL7
• Chromosome Location: 1p36.21
• Function: NOT amino acid transmembrane transporter activity; NOT folic acid transporter activity; NOT water channel activity