Recombinant Human POGLUT1 Protein, Myc/DDK-tagged, C13 and N15-labeled

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Recombinant Human POGLUT1 Protein, Myc/DDK-tagged, C13 and N15-labeled

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Cat.No. : POGLUT1-3323H
Product Overview : KTELC1 MS Standard C13 and N15-labeled recombinant protein (NP_064616) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.
Description : This gene encodes a protein with both O-glucosyltransferase and O-xylosyltransferase activity which localizes to the lumen of the endoplasmic reticulum. This protein has a carboxy-terminal KTEL motif which is predicted to function as an endoplasmic reticulum retention signal. This gene is an essential regulator of Notch signalling and likely plays a role in cell fate and tissue formation during development. It may also play a role in the pathogenesis of leukemia. Mutations in this gene have been associated with the autosomal dominant genodermatosis Dowling-Degos disease 4. Alternative splicing results in multiple transcript variants.
Source : HEK293
Species : Human
Tag : Myc/DDK
Molecular Mass : 46 kDa
AA Sequence : MEWWASSPLR LWLLLFLLPS AQGRQKESGS KWKVFIDQIN RSLENYEPCS SQNCSCYHGV IEEDLTPFRG GISRKMMAEV VRRKLGTHYQ ITKNRLYREN DCMFPSRCSG VEHFILEVIG RLPDMEMVIN VRDYPQVPKW MEPAIPVFSF SKTSEYHDIM YPAWTFWEGG PAVWPIYPTG LGRWDLFRED LVRSAAQWPW KKKNSTAYFR GSRTSPERDP LILLSRKNPK LVDAEYTKNQ AWKSMKDTLG KPAAKDVHLV DHCKYKYLFN FRGVAASFRF KHLFLCGSLV FHVGDEWLEF FYPQLKPWVH YIPVKTDLSN VQELLQFVKA NDDVAQEIAE RGSQFIRNHL QMDDITCYWE NLLSEYSKFL SYNVTRRKGY DQIIPKMLKT ELTRTRPLEQ KLISEEDLAA NDILDYKDDD DKV
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 3 months from receipt of products under proper storage and handling conditions.
Storage : Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
Concentration : 50 μg/mL as determined by BCA
Storage Buffer : 100 mM glycine, 25 mM Tris-HCl, pH 7.3.
SDS-PAGE :

Gene Name : POGLUT1 protein O-glucosyltransferase 1 [ Homo sapiens (human) ]
Official Symbol : POGLUT1
Synonyms : POGLUT1; protein O-glucosyltransferase 1; C3orf9, chromosome 3 open reading frame 9, KTEL (Lys Tyr Glu Leu) containing 1, KTELC1; 9630046K23Rik; hCLP46; KDELC family like 1; KDELCL1; MDS010; MDSRP; MGC32995; Rumi; x 010 protein; CAP10-like 46 kDa protein; CAP10-like protein, 46 kDa; KTEL motif-containing protein 1; KTEL (Lys-Tyr-Glu-Leu) containing 1; myelodysplastic syndromes relative protein; CLP46; C3orf9; KTELC1;
Gene ID : 56983
mRNA Refseq : NM_020231
Protein Refseq : NP_064616
MIM : 615618
UniProt ID : Q8NBL1

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