Recombinant Human POLM Protein (1-494 aa), His-Myc-tagged

• Cat.No.: POLM-2803H
• Product Overview: Recombinant Human POLM Protein (1-494 aa) is produced by Baculovirus expression system. This protein is fused with a 10xHis tag at the N-terminal and a Myc tag at the C-terminal. Protein Description: Full Length.

Specification

• Description: Gap-filling polymerase involved in repair of DNA double-strand breaks by non-homologous end joining (NHEJ). Participates in immunoglobulin (Ig) light chain gene rearrangement in V(D)J recombination.
• Source: Baculovirus
• Species: Human
• Tag: His-Myc
• Form: Tris-based buffer,50% glycerol
• Molecular Mass: 58.8 kDa
• Protein length: 1-494 aa
• AA Sequence: MLPKRRRARVGSPSGDAASSTPPST RFPGVAIYLVEPRMGRSRRAFLTGL ARSKGFRVLDACSSEATHVVMEETS AEEAVSWQERRMAAAPPGCTPPALL DISWLTESLGAGQPVPVECRHRLEV AGPRKGPLSPAWMPAYACQRPTPLT HHNTGLSEALEILAEAAGFEGSEGR LLTFCRAASVLKALPSPVTTLSQLQ GLPHFGEHSSRVVQELLEHGVCEEV ERVRRSERYQTMKLFTQIFGVGVKT ADRWYREGLRTLDDLREQPQKLTQQ QKAGLQHHQDLSTPVLRSDVDALQQ VVEEAVGQALPGATVTLTGGFRRGK LQGHDVDFLITHPKEGQEAGLLPRV MCRLQDQGLILYHQHQHSCCESPTR LAQQSHMDAFERSFCIFRLPQPPGA AVGGSTRPCPSWKAVRVDLVVAPVS QFPFALLGWTGSKLFQRELRRFSRK EKGLWLNSHGLFDPEQKTFFQAASE EDIFRHLGLEYLPPEQRNA
• Purity: > 85% as determined by SDS-PAGE.
• Notes: Repeated freezing and thawing is not recommended. Store working aliquots at 4 centigrade for up to one week.
• Storage: The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20 centigrade/-80 centigrade. The shelf life of lyophilized form is 12 months at -20 centigrade/-80 centigrade.
• Concentration: A hardcopy of COA will be sent along with the products. Please refer to it for detailed information.

Gene Information

• Gene Name: POLM polymerase (DNA directed), mu [ Homo sapiens ]
• Official Symbol: POLM
• Synonyms: POLM; polymerase (DNA directed), mu; Pol iota; Tdt N; DNA polymerase mu; terminal transferase; Tdt-N; Pol Mu; FLJ35482
• Gene ID: 27434
• mRNA Refseq: NM_013284
• Protein Refseq: NP_037416
• MIM: 606344
• UniProt ID: Q9NP87