Recombinant Human PPHLN1 Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: PPHLN1-961H
• Product Overview: PPHLN1 MS Standard C13 and N15-labeled recombinant protein (NP_958846) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: The protein encoded by this gene is one of the several proteins that become sequentially incorporated into the cornified cell envelope during the terminal differentiation of keratinocyte at the outer layers of epidermis. This protein interacts with periplakin, which is known as a precursor of the cornified cell envelope. The cellular localization pattern and insolubility of this protein suggest that it may play a role in epithelial differentiation and contribute to epidermal integrity and barrier formation. Multiple alternatively spliced transcript variants encoding distinct isoforms have been observed.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 29.8 kDa
• AA Sequence: MAYRRDEMWSEGRYEYERIPRERAP PRSHPSDESGYRWTRDDHSASRQPE YRDMRDGFRRKSFYSSHYARERSPY KRDNTFFRESPVGRKDSPHSRSGSS VSSRSYSPERSKSYSFHQSQHRKSV RPGASYKRQNEGNPERDKERPVQSL KTSRDTSPSSGSAVSSSKVLDKPSR LTEKELAEAASKWAAEKLEKSDESN LPEISEYEAGSTAPLFTDQPEEPES NTTHGIELFEDSQLTTRSKAIASKT KEIEQVRVTRTRPLEQKLISEEDLA ANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: PPHLN1 periphilin 1 [ Homo sapiens (human) ]
• Official Symbol: PPHLN1
• Synonyms: PPHLN1; periphilin 1; periphilin-1; gastric cancer antigen Ga50; HSPC206; HSPC232; MGC48786
• Gene ID: 51535
• mRNA Refseq: NM_201438
• Protein Refseq: NP_958846
• MIM: 608150
• UniProt ID: Q8NEY8