Recombinant Human PPM1B Protein, Myc/DDK-tagged, C13 and N15-labeled
Cat.No. : | PPM1B-2868H |
Product Overview : | PPM1B MS Standard C13 and N15-labeled recombinant protein (NP_808908) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells. |
- Specification
- Gene Information
- Related Products
Description : | The protein encoded by this gene is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase has been shown to dephosphorylate cyclin-dependent kinases (CDKs), and thus may be involved in cell cycle control. Overexpression of this phosphatase is reported to cause cell-growth arrest or cell death. Alternative splicing results in multiple transcript variants encoding different isoforms. Additional transcript variants have been described, but currently do not represent full-length sequences. |
Source : | HEK293 |
Species : | Human |
Tag : | Myc/DDK |
Molecular Mass : | 52.6 kDa |
AA Sequence : | MGAFLDKPKTEKHNAHGAGNGLRYG LSSMQGWRVEMEDAHTAVVGIPHGL EDWSFFAVYDGHAGSRVANYCSTHL LEHITTNEDFRAAGKSGSALELSVE NVKNGIRTGFLKIDEYMRNFSDLRN GMDRSGSTAVGVMISPKHIYFINCG DSRAVLYRNGQVCFSTQDHKPCNPR EKERIQNAGGSVMIQRVNGSLAVSR ALGDYDYKCVDGKGPTEQLVSPEPE VYEILRAEEDEFIILACDGIWDVMS NEELCEYVKSRLEVSDDLENVCNWV VDTCLHKGSRDNMSIVLVCFSNAPK VSDEAVKKDSELDKHLESRVEEIME KSGEEGMPDLAHVMRILSAENIPNL PPGGGLAGKRNVIEAVYSRLNPHRE SDGASDEAEESGSQGKLVEALRQMR INHRGNYRQLLEEMLTSYRLAKVEG EESPAEPAATATSSNSDAGNPVTMQ ESHTESESGLAELDSSNEDAGTKMS GEKITRTRPLEQKLISEEDLAANDI LDYKDDDDKV |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 3 months from receipt of products under proper storage and handling conditions. |
Storage : | Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
Concentration : | 50 μg/mL as determined by BCA |
Storage Buffer : | 100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
Gene Name : | PPM1B protein phosphatase, Mg2+/Mn2+ dependent 1B [ Homo sapiens (human) ] |
Official Symbol : | PPM1B |
Synonyms : | PPM1B; protein phosphatase, Mg2+/Mn2+ dependent, 1B; protein phosphatase 1B (formerly 2C), magnesium dependent, beta isoform; protein phosphatase 1B; PP2CB; PP2CBETA; PPC2BETAX; protein phosphatase 2C; beta isoform; PP2C-beta; protein phosphatase 2C isoform beta; protein phosphatase 2C-like protein; protein phosphatase 1B (formerly 2C), magnesium-dependent, beta isoform; PP2C-beta-X; MGC21657; |
Gene ID : | 5495 |
mRNA Refseq : | NM_177969 |
Protein Refseq : | NP_808908 |
MIM : | 603770 |
UniProt ID : | O75688 |
Products Types
◆ Recombinant Protein | ||
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PPM1B-1894H | Recombinant Human PPM1B, GST-tagged | +Inquiry |
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PPM1B-3552R | Recombinant Rhesus monkey PPM1B Protein, His-tagged | +Inquiry |
◆ Lysates | ||
PPM1B-2962HCL | Recombinant Human PPM1B 293 Cell Lysate | +Inquiry |
PPM1B-2963HCL | Recombinant Human PPM1B 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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