Recombinant Human PPM1F,GST-tagged
Cat.No. : | PPM1F-1439H |
Product Overview : | Recombinant full-length human CaMKPase was expressed inE. colicells using an N-terminal GST tag. MW = 74kDa. |
- Specification
- Gene Information
- Related Products
Cat. No. : | PPM1F-1439H |
Description : | CaMKPase is a member of the PP2C family of Ser/Thr protein phosphatases that dephosphorylate and regulate the multifunctional Ca2+/calmodulin-dependent protein kinases (CaMKs). The multifunctional CaMKs mediate cellular responses induced by increases in second messenger Ca2+ and have been implicated in the control of synaptic transmission, gene transcription, cell growth and contraction of cardiac and smooth muscles. Overexpression of CaMKPase has been shown to mediate caspase-dependent apoptosis. CaMKPase can also interact with the Rho guanine nucleotide exchange factors (PIX) thereby blocking the effects of p21-activated kinase 1 (PAK1). |
Source : | E. coli. |
Sequence : | Full-length. |
Applications : | Western Blot. |
Storage And Stability : | Store product at -70℃. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles. |
Gene Name : | PPM1F protein phosphatase 1F (PP2C domain containing) [ Homo sapiens ] |
Synonyms : | PPM1F; protein phosphatase 1F (PP2C domain containing); CAMKP; FEM-2; POPX2; hFEM-2; CaMKPase; KIAA0015 |
Gene ID : | 9647 |
mRNA Refseq : | NM_014634 |
Protein Refseq : | NP_055449 |
UniProt ID : | P49593 |
Chromosome Location : | 22q11.22 |
Function : | hydrolase activity; magnesium ion binding; manganese ion binding; protein serine/threonine phosphatase activity |
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PPM1F-31046TH | Recombinant Human PPM1F | +Inquiry |
◆ Lysates | ||
PPM1F-2961HCL | Recombinant Human PPM1F 293 Cell Lysate | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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