Recombinant Human PPP1R16B Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: PPP1R16B-3453H
• Product Overview: PPP1R16B MS Standard C13 and N15-labeled recombinant protein (NP_056383) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Species: Human
• Source: HEK293
• Tag: DDK&Myc
• Description: The protein encoded by this gene is membrane-associated and contains five ankyrin repeats, a protein phosphatase-1-interacting domain, and a carboxy-terminal CAAX box domain. Synthesis of the encoded protein is inhibited by transforming growth factor beta-1. The protein may bind to the membrane through its CAAX box domain and may act as a signaling molecule through interaction with protein phosphatase-1. Alternative splicing results in multiple transcript variants encoding different isoforms that may undergo similar processing to generate mature protein.
• Molecular Mass: 63.4 kDa
• AA Sequence: MASHVDLLTELQLLEKVPTLERLRAAQKRRAQQLKKWAQYEQDLQHRKRKHERKRSTGGRRKKVSFEASVALLEASLRNDAEEVRYFLKNKVSPDLCNEDGLTALHQCCIDNFEEIVKLLLSHGANVNAKDNELWTPLHAAATCGHINLVKILVQYGADLLAVNSDGNMPYDLCEDEPTLDVIETCMAYQGITQEKINEMRVAPEQQMIADIHCMIAAGQDLDWIDAQGATLLHIAGANGYLRAAELLLDHGVRVDVKDWDGWEPLHAAAFWGQMQMAELLVSHGASLSARTSMDEMPIDLCEEEEFKVLLLELKHKHDVIMKSQLRHKSSLSRRTSSAGSRGKVVRRASLSDRTNLYRKEYEGEAILWQRSAAEDQRTSTYNGDIRETRTDQENKDPNPRLEKPVLLSEFPTKIPRGELDMPVENGLRAPVSAYQYALANGDVWKVHEVPDYSMAYGNPGVADATPPWSSYKEQSPQTLLELKRQRAAAKLLSHPFLSTHLGSSMARTGESSSEGKAPLIGGRTSPYSSNGTSVYYTVTSGDPPLLKFKAPIEEMEEKVHGCCRISTRTRPLEQKLISEEDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: PPP1R16B protein phosphatase 1 regulatory subunit 16B [ Homo sapiens (human) ]
• Official Symbol: PPP1R16B
• Synonyms: PPP1R16B; protein phosphatase 1, regulatory subunit 16B; protein phosphatase 1, regulatory (inhibitor) subunit 16B; protein phosphatase 1 regulatory inhibitor subunit 16B; ANKRD4; ankyrin repeat domain protein 4; KIAA0823; TGF beta inhibited membrane associated protein; TIMAP; hTIMAP; CAAX box protein TIMAP; ankyrin repeat domain-containing protein 4; TGF-beta-inhibited membrane-associated protein
• Gene ID: 26051
• mRNA Refseq: NM_015568
• Protein Refseq: NP_056383
• MIM: 613275
• UniProt ID: Q96T49