| Description : |
This gene encodes a scaffold protein that functions as a regulatory subunit of protein phosphatase 1a. Expression of this gene is particularly high in dendritic spines, suggesting that the encoded protein may play a role in receiving signals from the central nervous system. The encoded protein has putative tumor suppressor function and decreased expression has been observed in tumors. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
89.2 kDa |
| AA Sequence : |
MMKTEPRGPGGPLRSASPHRSAYEA GIQALKPPDAPGPDEAPKGAHHKKY GSNVHRIKSMFLQMGTTAGPSGEAG GGAGLAEAPRASERGVRLSLPRASS LNENVDHSALLKLGTSVSERVSRFD SKPAPSAQPAPPPHPPSRLQETRKL FERSAPAAAGGDKEAAARRLLRQER AGLQDRKLDVVVRFNGSTEALDKLD ADAVSPTVSQLSAVFEKADSRTGLH RGPGLPRAAGVPQVNSKLVSKRSRV FQPPPPPPPAPSGDAPAEKERCPAG QQPPQHRVAPARPPPKPREVRKIKP VEVEESGESEAESAPGEVIQAEVTV HAALENGSTVATAASPAPEEPKAQA APEKEAAAVAPPERGVGNGRAPDVA PEEVDESKKEDFSEADLVDVSAYSG LGEDSAGSALEEDDEDDEEDGEPPY EPESGCVEIPGLSEEEDPAPSRKIH FSTAPIQVFSTYSNEDYDRRNEDVD PMAASAEYELEKRVERLELFPVELE KDSEGLGISIIGMGAGADMGLEKLG IFVKTVTEGGAAHRDGRIQVNDLLV EVDGTSLVGVTQSFAASVLRNTKGR VRFMIGRERPGEQSEVAQLIQQTLE QERWQREMMEQRYAQYGEDDEETGE YATDEDEELSPTFPGGEMAIEVFEL AENEDALSPVDMEPEKLVHKFKELQ IKHAVTEAEIQQLKRKLQSLEQEKG RWRVEKAQLEQSVEENKERMEKLEG YWGEAQSLCQAVDEHLRETQAQYQA LERKYSKAKRLIKDYQQKEIEFLKK ETAQRRVLEESELARKEEMDKLLDK ISELEGNLQTLRNSNSTTRTRPLEQ KLISEEDLAANDILDYKDDDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
