| Description : |
The protein encoded by this gene is a regulatory protein for the protein phosphatase-6 catalytic subunit. Together, these proteins act as a significant T-loop phosphatase for Aurora A, an essential mitotic kinase. Loss of function of either the regulatory or catalytic subunit of protein phosphatase-6 interferes with spindle formation and chromosome alignment. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
101.4 kDa |
| AA Sequence : |
MFWKFDLNTTSHVDKLLDKEHVTLQ ELMDEDDILQECKAQNQKLLDFLCR QQCMEELVSLITQDPPLDMEEKVRF KYPNTACELLTCDVPQISDRLGGDE SLLSLLYDFLDHEPPLNPLLASFFS KTIGNLIARKTEQVITFLKKKDKFI SLVLKHIGTSALMDLLLRLVSCVEP AGLRQDVLHWLNEEKVIQRLVELIH PSQDEDRQSNASQTLCDIVRLGRDQ GSQLQEALEPDPLLTALESRQDCVE QLLKNMFDGDRTESCLVSGTQVLLT LLETRRVGTEGLVDSFSQGLERSYA VSSSVLHGIEPRLKDFHQLLLNPPK KKAILTTIGVLEEPLGNARLHGARL MAALLHTNTPSINQELCRLNTMDLL LDLFFKYTWNNFLHFQVELCIAAIL SHAAREERTEASGSESRVEPPHENG NRSLETPQPAASLPDNTMVTHLFQK CCLVQRILEAWEANDHTQAAGGMRR GNMGHLTRIANAVVQNLERGPVQTH ISEVIRGLPADCRGRWESFVEETLT ETNRRNTVDLAFSDYQIQQMTANFV DQFGFNDEEFADQDDNINAPFDRIA EINFNIDADEDSPSAALFEACCSDR IQPFDDDEDEDIWEDSDTRCAARVM ARPRFGAPHASESCSKNGPERGGQD GKASLEAHRDAPGAGAPPAPGKKEA PPVEGDSEGAMWTAVFDEPANSTPT APGVVRDVGSSVWAAGTSAPEEKGW AKFTDFQPFCCSESGPRCSSPVDTE CSHAEGSRSQGPEKAFSPASPCAWN VCVTRKAPLLASDSSSSGGSHSEDG DQKAASAMDAVSRGPGREAPPLPTV ARTEEAVGRVGCADSRLLSPACPAP KEVTAAPAVAVPPEATVAITTALSK AGPAIPTPAVSSALAVAVPLGPIMA VTAAPAMVATLGTVTKDGKTDAPPE GAALNGPVTRTRPLEQKLISEEDLA ANDILDYKDDDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
