Recombinant Human PRDX3 Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: PRDX3-4361H
• Product Overview: PRDX3 MS Standard C13 and N15-labeled recombinant protein (NP_006784) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Species: Human
• Source: HEK293
• Tag: DDK&Myc
• Description: This gene encodes a mitochondrial protein with antioxidant function. The protein is similar to the C22 subunit of Salmonella typhimurium alkylhydroperoxide reductase, and it can rescue bacterial resistance to alkylhydroperoxide in E. coli that lack the C22 subunit. The human and mouse genes are highly conserved, and they map to the regions syntenic between mouse and human chromosomes. Sequence comparisons with recently cloned mammalian homologs suggest that these genes consist of a family that is responsible for the regulation of cellular proliferation, differentiation and antioxidant functions. This family member can protect cells from oxidative stress, and it can promote cell survival in prostate cancer. Alternative splicing of this gene results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 1, 3, 13 and 22.
• Molecular Mass: 27.7 kDa
• AA Sequence: MAAAVGRLLRASVARHVSAIPWGISATAALRPAACGRTSLTNLLCSGSSQAKLFSTSSSCHAPAVTQHAPYFKGTAVVNGEFKDLSLDDFKGKYLVLFFYPLDFTFVCPTEIVAFSDKANEFHDVNCEVVAVSVDSHFSHLAWINTPRKNGGLGHMNIALLSDLTKQISRDYGVLLEGSGLALRGLFIIDPNGVIKHLSVNDLPVGRSVEETLRLVKAFQYVETHGEVCPANWTPDSPTIKPSPAASKEYFQKVNQTRTRPLEQKLISEEDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: PRDX3 peroxiredoxin 3 [ Homo sapiens (human) ]
• Official Symbol: PRDX3
• Synonyms: PRDX3; peroxiredoxin 3; antioxidant protein 1, AOP1; thioredoxin-dependent peroxide reductase, mitochondrial; AOP 1; MER5; SP 22; peroxiredoxin-3; peroxiredoxin III; protein MER5 homolog; antioxidant protein 1; AOP1; AOP-1; SP-22; HBC189; PRO1748; prx-III; MGC24293; MGC104387
• Gene ID: 10935
• mRNA Refseq: NM_006793
• Protein Refseq: NP_006784
• MIM: 604769
• UniProt ID: P30048